SEM1_ASHGO
ID SEM1_ASHGO Reviewed; 69 AA.
AC P62499; Q756K1;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Probable 26S proteasome complex subunit SEM1;
GN Name=SEM1; OrderedLocusNames=AER253W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Subunit of the 26S proteasome which plays a role in
CC ubiquitin-dependent proteolysis. {ECO:0000250}.
CC -!- SUBUNIT: Part of the 26S proteasome. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DSS1/SEM1 family. {ECO:0000305}.
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DR EMBL; AE016818; AAS52934.1; -; Genomic_DNA.
DR RefSeq; NP_985110.1; NM_210464.2.
DR AlphaFoldDB; P62499; -.
DR SMR; P62499; -.
DR STRING; 33169.AAS52934; -.
DR EnsemblFungi; AAS52934; AAS52934; AGOS_AER253W.
DR GeneID; 4621320; -.
DR KEGG; ago:AGOS_AER253W; -.
DR eggNOG; KOG4764; Eukaryota.
DR HOGENOM; CLU_141774_1_0_1; -.
DR InParanoid; P62499; -.
DR OMA; TLWENNW; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0000502; C:proteasome complex; IBA:GO_Central.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:EnsemblFungi.
DR GO; GO:0034515; C:proteasome storage granule; IEA:EnsemblFungi.
DR GO; GO:0070390; C:transcription export complex 2; IEA:EnsemblFungi.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0030447; P:filamentous growth; IEA:EnsemblFungi.
DR GO; GO:0016578; P:histone deubiquitination; IEA:EnsemblFungi.
DR GO; GO:0035753; P:maintenance of DNA trinucleotide repeats; IEA:EnsemblFungi.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0043248; P:proteasome assembly; IEA:EnsemblFungi.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:EnsemblFungi.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:EnsemblFungi.
DR GO; GO:0072742; P:SAGA complex localization to transcription regulatory region; IEA:EnsemblFungi.
DR InterPro; IPR007834; DSS1_SEM1.
DR PANTHER; PTHR16771; PTHR16771; 1.
DR Pfam; PF05160; DSS1_SEM1; 1.
DR SMART; SM01385; DSS1_SEM1; 1.
PE 3: Inferred from homology;
KW Proteasome; Reference proteome.
FT CHAIN 1..69
FT /note="Probable 26S proteasome complex subunit SEM1"
FT /id="PRO_0000122967"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 69 AA; 8100 MW; 052D15CB5E88F723 CRC64;
MSDKPATPTK HALEDEDEFE DFPVDSWPST ETLKAYKEGD SCLWEEDWDD VEVEDDFTKE
LKKELESNK
