ID   SEM1_DICDI              Reviewed;          76 AA.
AC   Q54K21;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Probable 26S proteasome complex subunit sem1;
GN   ORFNames=DDB_G0287633;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Subunit of the 26S proteasome which plays a role in
CC       ubiquitin-dependent proteolysis. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 26S proteasome. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DSS1/SEM1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000103; EAL63625.1; -; Genomic_DNA.
DR   RefSeq; XP_637143.1; XM_632051.1.
DR   AlphaFoldDB; Q54K21; -.
DR   SMR; Q54K21; -.
DR   STRING; 44689.DDB0231348; -.
DR   PaxDb; Q54K21; -.
DR   EnsemblProtists; EAL63625; EAL63625; DDB_G0287633.
DR   GeneID; 8626238; -.
DR   KEGG; ddi:DDB_G0287633; -.
DR   dictyBase; DDB_G0287633; -.
DR   eggNOG; ENOG502RICK; Eukaryota.
DR   HOGENOM; CLU_141774_1_1_1; -.
DR   InParanoid; Q54K21; -.
DR   OMA; EDWVENE; -.
DR   PRO; PR:Q54K21; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0000502; C:proteasome complex; IBA:GO_Central.
DR   GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0043248; P:proteasome assembly; IEA:InterPro.
DR   InterPro; IPR007834; DSS1_SEM1.
DR   PANTHER; PTHR16771; PTHR16771; 1.
DR   Pfam; PF05160; DSS1_SEM1; 1.
DR   SMART; SM01385; DSS1_SEM1; 1.
PE   3: Inferred from homology;
KW   Proteasome; Reference proteome.
FT   CHAIN           1..76
FT                   /note="Probable 26S proteasome complex subunit sem1"
FT                   /id="PRO_0000345009"
FT   REGION          30..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..55
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   76 AA;  8973 MW;  6D331D333FC0EF75 CRC64;
     MTKTETKVEP KAEVKPKEDN VEVIEDDEFE EFEDNMAEGE DNSKEQWEDD WDTDKIDDDF
     SKQLRAEIES HSTMKS