ID   SEMA_ALHV1              Reviewed;         653 AA.
AC   Q77ZF8;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   02-DEC-2020, entry version 40.
DE   RecName: Full=Semaphorin-like protein A3;
GN   Name=A3;
OS   Alcelaphine herpesvirus 1 (strain C500) (AlHV-1) (Malignant catarrhal fever
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Macavirus.
OX   NCBI_TaxID=654901;
OH   NCBI_TaxID=9927; Connochaetes taurinus (Blue wildebeest).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9261371; DOI=10.1128/jvi.71.9.6517-6525.1997;
RA   Ensser A., Pflanz R., Fleckenstein B.;
RT   "Primary structure of the alcelaphine herpesvirus 1 genome.";
RL   J. Virol. 71:6517-6525(1997).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=9049359; DOI=10.1099/0022-1317-76-4-1063;
RA   Ensser A., Fleckenstein B.;
RT   "Alcelaphine herpesvirus type 1 has a semaphorin-like gene.";
RL   J. Gen. Virol. 76:1063-1067(1995).
CC   -!- FUNCTION: May act as an immune modulator in host-infected cells.
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DR   EMBL; AF005370; AAC58054.1; -; Genomic_DNA.
DR   PIR; T03102; T03102.
DR   RefSeq; NP_065506.1; NC_002531.1.
DR   SMR; Q77ZF8; -.
DR   GeneID; 911790; -.
DR   KEGG; vg:911790; -.
DR   Proteomes; UP000000941; Genome.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   Gene3D; 2.130.10.10; -; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; PTHR11036; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF101912; SSF101912; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Disulfide bond; Reference proteome.
FT   CHAIN           1..653
FT                   /note="Semaphorin-like protein A3"
FT                   /id="PRO_0000405698"
FT   DOMAIN          76..512
FT                   /note="Sema"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00352"
FT   DOMAIN          514..563
FT                   /note="PSI"
FT   DISULFID        587..634
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114,
FT                   ECO:0000255|PROSITE-ProRule:PRU00352"
SQ   SEQUENCE   653 AA;  73646 MW;  5C2816BD567E706E CRC64;
     MAYLNATVSK PVISLLSLSK KVLKFEHCGG EGQCLGLITE FVIHPAAMGT LCVSIRLLMI
     LSAITAAKSR FIDKPRLIVN LTDGFGQHRF FGPQEPHTVL FHSLNSSDVY VGGNNTIYLF
     DFAHSSNAST ALINITSTHN THRLSSTCEN FITLLHNQTD GLLACGTNSQ KPSCWLINNL
     TTQFLGPKLG LAPFSPSSGN LVLFDQNDTY STINLYKSLS GSHKFRRIAG QVELYTSDTA
     MHRPQFVQAT AVHKNESYDD KIYFFFQENS HSDFKQFPHT VPRVGQVCSS DQGGESSLSV
     YKWTTFLKAR LACVDYDTGR IYNELQDIFI WQAPENSWEE TLIYGLFLSP WNFSAVCVFT
     VKDIDHVFKT SKLKNYHHKL PTPRPGQCMK NHQHVPTETF QVADRYPEVA DPVYQKNNAM
     FPIIQSKYIY TKLLVYRVEY GGVFWATIFY LTTIKGTIHI YVRYEDSNST TALNILEINP
     FQKPAPIQNI LLDNTNLKLY VNSEWEVSEV PLDLCSVYGN DCFSCFMSRD PLCTWYNNTC
     SFKQRVSVET GGPANRTLSE MCGDHYAPTV VKHQVSIPLL SNSYLSCPAV SNHADYFWTK
     DGFTEKRCHV KTHKNDCILL IANSTTATNG THVCNMKEDS VTVKLLEVNV TLM