ID   SEMA_VAR67              Reviewed;         122 AA.
AC   Q76QZ8;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Semaphorin-like protein A43;
GN   Name=A43R;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7856312; DOI=10.1016/0168-1702(94)90125-2;
RA   Shchelkunov S.N., Blinov V.M., Resenchuk S.M., Totmenin A.V., Olenina L.V.,
RA   Chirikova G.B., Sandakhchiev L.S.;
RT   "Analysis of the nucleotide sequence of 53 kbp from the right terminus of
RT   the genome of variola major virus strain India-1967.";
RL   Virus Res. 34:207-236(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7597802; DOI=10.1007/bf01702879;
RA   Shchelkunov S.N., Totmenin A.V.;
RT   "Two types of deletions in orthopoxvirus genomes.";
RL   Virus Genes 9:231-245(1995).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=India-1967;
RX   PubMed=8725113; DOI=10.1016/0168-1702(95)01269-9;
RA   Shchelkunov S.N., Totmenin A.V., Sandakhchiev L.S.;
RT   "Analysis of the nucleotide sequence of 23.8 kbp from the left terminus of
RT   the genome of variola major virus strain India-1967.";
RL   Virus Res. 40:169-183(1996).
CC   -!- MISCELLANEOUS: Variola virus encodes a likely non-functional truncated
CC       version of the semaphorin-like protein.
CC   -!- SIMILARITY: Belongs to the semaphorin family. {ECO:0000305}.
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DR   EMBL; X69198; CAA49090.1; -; Genomic_DNA.
DR   RefSeq; NP_042193.1; NC_001611.1.
DR   SMR; Q76QZ8; -.
DR   GeneID; 1486524; -.
DR   KEGG; vg:1486524; -.
DR   Proteomes; UP000002060; Genome.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   Pfam; PF01403; Sema; 1.
DR   SUPFAM; SSF101912; SSF101912; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..122
FT                   /note="Semaphorin-like protein A43"
FT                   /id="PRO_0000412613"
FT   DOMAIN          1..122
FT                   /note="Sema"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00352"
SQ   SEQUENCE   122 AA;  14301 MW;  62C79BB3643F86BC CRC64;
     MIYLYTADNV IPKDGLQGAF VDKDGTYDKV YILFTVTIGS KRIVKIPYIA QMCLNDECGP
     SSLSSHRWST LLKVELECDI DGRSYSQINH SKTIKQIMIR YYMYSLIVLF QVRIMYLFYE
     YH