ID   SEOA_ARATH              Reviewed;         822 AA.
AC   Q93XX2; Q9SS88;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Protein SIEVE ELEMENT OCCLUSION A {ECO:0000303|PubMed:20932300};
DE            Short=AtSEOa {ECO:0000303|PubMed:20932300};
DE   AltName: Full=Protein SIEVE ELEMENT OCCLUSION-RELATED 2 {ECO:0000303|PubMed:22470058};
DE            Short=AtSEOR2 {ECO:0000303|PubMed:22470058};
GN   Name=SEOA {ECO:0000303|PubMed:20932300};
GN   Synonyms=SEOR2 {ECO:0000303|PubMed:22470058};
GN   OrderedLocusNames=At3g01670 {ECO:0000312|Araport:AT3G01670};
GN   ORFNames=F4P13.21 {ECO:0000312|EMBL:AAF01550.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP   NOMENCLATURE.
RX   PubMed=20932300; DOI=10.1186/1471-2229-10-219;
RA   Ruping B., Ernst A.M., Jekat S.B., Nordzieke S., Reineke A.R., Muller B.,
RA   Bornberg-Bauer E., Prufer D., Noll G.A.;
RT   "Molecular and phylogenetic characterization of the sieve element occlusion
RT   gene family in Fabaceae and non-Fabaceae plants.";
RL   BMC Plant Biol. 10:219-219(2010).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, SUBUNIT, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=22470058; DOI=10.1093/pcp/pcs046;
RA   Anstead J.A., Froelich D.R., Knoblauch M., Thompson G.A.;
RT   "Arabidopsis P-protein filament formation requires both AtSEOR1 and
RT   AtSEOR2.";
RL   Plant Cell Physiol. 53:1033-1042(2012).
CC   -!- FUNCTION: Scaffold protein required to form the phloem filament matrix
CC       in sieve elements. {ECO:0000269|PubMed:22470058}.
CC   -!- SUBUNIT: Can form homodimer. {ECO:0000269|PubMed:22470058}.
CC   -!- INTERACTION:
CC       Q93XX2; Q9SJG9: MPK20; NbExp=3; IntAct=EBI-4424691, EBI-2358896;
CC       Q93XX2; Q42536: PORA; NbExp=4; IntAct=EBI-4424691, EBI-4424685;
CC   -!- TISSUE SPECIFICITY: Expressed in phloem sieve elements.
CC       {ECO:0000269|PubMed:20932300}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC       conditions. {ECO:0000269|PubMed:22470058}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF01550.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; HM162885; ADN32813.1; -; mRNA.
DR   EMBL; AC009325; AAF01550.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP002686; AEE73701.1; -; Genomic_DNA.
DR   EMBL; AY059845; AAL24327.1; -; mRNA.
DR   EMBL; BT008797; AAP68236.1; -; mRNA.
DR   RefSeq; NP_001325831.1; NM_001337353.1.
DR   RefSeq; NP_566145.1; NM_111033.3.
DR   AlphaFoldDB; Q93XX2; -.
DR   SMR; Q93XX2; -.
DR   IntAct; Q93XX2; 19.
DR   STRING; 3702.AT3G01670.1; -.
DR   iPTMnet; Q93XX2; -.
DR   PaxDb; Q93XX2; -.
DR   PRIDE; Q93XX2; -.
DR   EnsemblPlants; AT3G01670.1; AT3G01670.1; AT3G01670.
DR   GeneID; 821096; -.
DR   Gramene; AT3G01670.1; AT3G01670.1; AT3G01670.
DR   KEGG; ath:AT3G01670; -.
DR   Araport; AT3G01670; -.
DR   TAIR; locus:2084143; AT3G01670.
DR   eggNOG; ENOG502QS6Q; Eukaryota.
DR   HOGENOM; CLU_025476_0_0_1; -.
DR   InParanoid; Q93XX2; -.
DR   OrthoDB; 160769at2759; -.
DR   PRO; PR:Q93XX2; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q93XX2; baseline and differential.
DR   Genevisible; Q93XX2; AT.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IPI:TAIR.
DR   GO; GO:0010088; P:phloem development; IMP:UniProtKB.
DR   InterPro; IPR027944; SEO_C.
DR   InterPro; IPR027942; SEO_N.
DR   InterPro; IPR039299; SEOA.
DR   PANTHER; PTHR33232; PTHR33232; 1.
DR   Pfam; PF14577; SEO_C; 1.
DR   Pfam; PF14576; SEO_N; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..822
FT                   /note="Protein SIEVE ELEMENT OCCLUSION A"
FT                   /id="PRO_0000432873"
FT   REGION          25..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   822 AA;  94217 MW;  65952FE0A9274B8F CRC64;
     MAQRFQLNSQ TLPTADPLKR VSLIPRSAEQ RLADNAGERR PLAPRSHEDN PFGGHTDDHH
     VAAPADHNKV MDHNSENLGS IVPKTAHYPH PSEEILDANI RHSMVPKSLG PNSLGGRFGP
     GKKQAFHRNG RPMFSLSDDR VMADRVLKTH SPDMIFFDVT SLLSVVNDIF KSHVPSIDSS
     APKPSLVFKD YADHTSFETF ADLIDQISCE IDCKCLHGGE SHGMMTSGLH LDSRNTTTFS
     VLSLVSKYRW DAKLVLVLSA LAVKYGVFLL LAETHATNQL TKSLALIKQL PSIFSRQNAL
     HQRLDKTRIL MQDMVDLTTT IIDIYQLPPN HITAAFTDHI PTAVYWIVRC VLICVSHISG
     ASGFKQDQIM SFMEVSEIHE NSERLRKINA YLLEQFKKSK MTIEEGIIEE EYQELIQTFT
     TIIHVDVVPP LLRLLRPIDF LYHGAGVSKR RVGINVLTQK HVLLLISDLE NIEKELYILE
     SLYTEAWQQS FEILWVPVQD FWTEADDAKF EALHMNMRWY VLGEPRKLRR AAIRFVREWW
     GFKNRPILVA LDPKGQVMST NAFPMVWIWQ PFAHPFTTAR ERDLWSEQEW NLEFLIDGTD
     PHSLNQLVDG KYICLYGGED MQWIKNFTSL WRNVAKAANI QLEMVYVGKR NPKNGIQPII
     NTIREENLSH TLPDLFQIWF FWTRVESMWE SKQRMLKAHG IKGREGFKEE EKDLVLQEVV
     AMLGYGGEGD GWGLVSKASD MMVRAKGNLF SRGLAEFNEW EVNIPTKGFL TALNDHLLMR
     LPPHHCTRFM LPETAGIIPN EVECTECRRT MEKYYLYQCC LE