ID   SEPC_PSEP1              Reviewed;         480 AA.
AC   Q849R1; A5W4E0;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Probable efflux pump outer membrane protein SepC;
DE   Flags: Precursor;
GN   Name=sepC; OrderedLocusNames=Pput_2869;
OS   Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=351746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9037074; DOI=10.1073/pnas.94.4.1453;
RA   Lau P.C., Wang Y., Patel A., Labbe D., Bergeron H., Brousseau R.,
RA   Konishi Y., Rawlings M.;
RT   "A bacterial basic region leucine zipper histidine kinase regulating
RT   toluene degradation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 94:1453-1458(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700007 / DSM 6899 / BCRC 17059 / F1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Lykidis A., Parales R., Richardson P.;
RT   "Complete sequence of Pseudomonas putida F1.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable outer membrane component of the SepABC efflux pump
CC       with unknown specificity.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000305}.
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DR   EMBL; U72354; AAO49778.1; -; Genomic_DNA.
DR   EMBL; CP000712; ABQ79000.1; -; Genomic_DNA.
DR   RefSeq; WP_012052589.1; NC_009512.1.
DR   AlphaFoldDB; Q849R1; -.
DR   SMR; Q849R1; -.
DR   STRING; 351746.Pput_2869; -.
DR   EnsemblBacteria; ABQ79000; ABQ79000; Pput_2869.
DR   KEGG; ppf:Pput_2869; -.
DR   eggNOG; COG1538; Bacteria.
DR   HOGENOM; CLU_012817_13_3_6; -.
DR   OMA; AQYERTI; -.
DR   OrthoDB; 1619477at2; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003423; OMP_efflux.
DR   InterPro; IPR010131; RND_efflux_OM_lipoprot_NodT.
DR   Pfam; PF02321; OEP; 2.
DR   TIGRFAMs; TIGR01845; outer_NodT; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal;
KW   Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..480
FT                   /note="Probable efflux pump outer membrane protein SepC"
FT                   /id="PRO_0000031006"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CONFLICT        438..440
FT                   /note="ELF -> DVV (in Ref. 1; AAO49778)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   480 AA;  52890 MW;  46E264EC2EE11352 CRC64;
     MKTHYLSIAL SVALSGCSLI PDYQRPPAPI QAGWPQGEAY AKLKAGTHRP SQTRDAELNW
     QVFFRDPVMR ELIATALNNN RDLRQTALNV EAYRALHRIE RSALLPRANT GVGATRQRLP
     ADLSPTGEAG IQSQYDTTLS MSYELDMFGR LRSLERAALQ EYLAAAETQR SMQIALIADV
     AIAYLSWRSD QAQLDLARST LASYENSLNL IKSSREVGTA SALDVRQARS LVETARVQQT
     LYTRQVAQDM NALQLLLGTK LPADLPISDV LDQPLAALST GLPADLLLHR PDIRAAEHRL
     LAANANIGAA RAAFFPSITL TAAAGTASHE LDGLFEGGSG LWAFMPRINL PIFTAGRLRG
     NLDYRNVIKD INVAEYEKSI QTAFREVADG LAARGTFGEQ LQAQRDLVDN NQAYYKLAYQ
     RYDEGVDNYL AVLDAQRELF AAQQQFLSDR LNQLSSEVRL FKALGGGWDN ISSQPLTAQN