ID   SEPF_LACLA              Reviewed;         196 AA.
AC   Q9CEH4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Cell division protein SepF {ECO:0000255|HAMAP-Rule:MF_01197};
GN   Name=sepF {ECO:0000255|HAMAP-Rule:MF_01197}; OrderedLocusNames=LL1867;
GN   ORFNames=L119731;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Cell division protein that is part of the divisome complex
CC       and is recruited early to the Z-ring. Probably stimulates Z-ring
CC       formation, perhaps through the cross-linking of FtsZ protofilaments.
CC       Its function overlaps with FtsA. {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01197}.
CC       Note=Localizes to the division site, in a FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SIMILARITY: Belongs to the SepF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
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DR   EMBL; AE005176; AAK05965.1; -; Genomic_DNA.
DR   PIR; C86858; C86858.
DR   RefSeq; NP_268024.1; NC_002662.1.
DR   RefSeq; WP_003132390.1; NC_002662.1.
DR   AlphaFoldDB; Q9CEH4; -.
DR   SMR; Q9CEH4; -.
DR   STRING; 272623.L119731; -.
DR   PaxDb; Q9CEH4; -.
DR   DNASU; 1115532; -.
DR   EnsemblBacteria; AAK05965; AAK05965; L119731.
DR   GeneID; 60355295; -.
DR   GeneID; 66442872; -.
DR   KEGG; lla:L119731; -.
DR   PATRIC; fig|272623.7.peg.2001; -.
DR   eggNOG; COG1799; Bacteria.
DR   HOGENOM; CLU_078499_2_0_9; -.
DR   OMA; ASERHYQ; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.150; -; 1.
DR   HAMAP; MF_01197; SepF; 1.
DR   InterPro; IPR023052; Cell_div_SepF.
DR   InterPro; IPR007561; Cell_div_SepF/SepF-rel.
DR   InterPro; IPR038594; SepF-like_sf.
DR   PANTHER; PTHR35798; PTHR35798; 1.
DR   Pfam; PF04472; SepF; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome; Septation.
FT   CHAIN           1..196
FT                   /note="Cell division protein SepF"
FT                   /id="PRO_0000334029"
FT   REGION          16..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  21870 MW;  6B9AE7EFE51363C0 CRC64;
     MAFKDWMNNL RDYFVEDDEE FNEPARPVQE SRPTVASTPK PKVEERKAQP EYQTRRPAQS
     TSKAQTQTAA PKRAGSTFTK PMPEKIVQQQ TVSQSQSVAA TVSTIAIKEP RAYADIMESA
     RIVKNGECVL VNFKFMGDAQ ARRSIDFMTG VVFTLDGDIQ NVGGQIFLMT PANITVDAAK
     EMSILAGQNF ESYDIY