ID   SEPF_MACCJ              Reviewed;         173 AA.
AC   B9EB57;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Cell division protein SepF {ECO:0000255|HAMAP-Rule:MF_01197};
GN   Name=sepF {ECO:0000255|HAMAP-Rule:MF_01197}; OrderedLocusNames=MCCL_0761;
OS   Macrococcus caseolyticus (strain JCSC5402).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Macrococcus.
OX   NCBI_TaxID=458233;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC5402;
RX   PubMed=19074389; DOI=10.1128/jb.01058-08;
RA   Baba T., Kuwahara-Arai K., Uchiyama I., Takeuchi F., Ito T., Hiramatsu K.;
RT   "Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402,
RT   reflecting the ancestral genome of the human-pathogenic staphylococci.";
RL   J. Bacteriol. 191:1180-1190(2009).
CC   -!- FUNCTION: Cell division protein that is part of the divisome complex
CC       and is recruited early to the Z-ring. Probably stimulates Z-ring
CC       formation, perhaps through the cross-linking of FtsZ protofilaments.
CC       Its function overlaps with FtsA. {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01197}.
CC       Note=Localizes to the division site, in a FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SIMILARITY: Belongs to the SepF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
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DR   EMBL; AP009484; BAH17468.1; -; Genomic_DNA.
DR   RefSeq; WP_012656669.1; NC_011999.1.
DR   AlphaFoldDB; B9EB57; -.
DR   SMR; B9EB57; -.
DR   STRING; 458233.MCCL_0761; -.
DR   EnsemblBacteria; BAH17468; BAH17468; MCCL_0761.
DR   GeneID; 61129341; -.
DR   KEGG; mcl:MCCL_0761; -.
DR   eggNOG; COG1799; Bacteria.
DR   HOGENOM; CLU_078499_4_1_9; -.
DR   OMA; ASERHYQ; -.
DR   OrthoDB; 2064885at2; -.
DR   Proteomes; UP000001383; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.150; -; 1.
DR   HAMAP; MF_01197; SepF; 1.
DR   InterPro; IPR023052; Cell_div_SepF.
DR   InterPro; IPR007561; Cell_div_SepF/SepF-rel.
DR   InterPro; IPR038594; SepF-like_sf.
DR   PANTHER; PTHR35798; PTHR35798; 1.
DR   Pfam; PF04472; SepF; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome; Septation.
FT   CHAIN           1..173
FT                   /note="Cell division protein SepF"
FT                   /id="PRO_1000164537"
SQ   SEQUENCE   173 AA;  19797 MW;  D4C6C1871A27663D CRC64;
     MAFKDVFKGF FAYEDEEVYV EEQSDKVREP AQKKVVKETY VPEKKVVRTE SFQKQSKPKM
     KVNEEKVTKA NVVNMHDDIV NVSSKVCLFE PRVFSDTQDI ADELKNRRAT LVNLQRIDKI
     SAKRIIDFLS GTVYAIGGDI QRIGQDIFLC TPDNVEVAGT ITEMLEAPEE ENE