ID   SEPF_NOCFA              Reviewed;         280 AA.
AC   Q5YYX3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Cell division protein SepF {ECO:0000255|HAMAP-Rule:MF_01197};
GN   Name=sepF {ECO:0000255|HAMAP-Rule:MF_01197}; OrderedLocusNames=NFA_17720;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- FUNCTION: Cell division protein that is part of the divisome complex
CC       and is recruited early to the Z-ring. Probably stimulates Z-ring
CC       formation, perhaps through the cross-linking of FtsZ protofilaments.
CC       Its function overlaps with FtsA. {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01197}.
CC       Note=Localizes to the division site, in a FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01197}.
CC   -!- SIMILARITY: Belongs to the SepF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01197}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD56618.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AP006618; BAD56618.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041560009.1; NC_006361.1.
DR   AlphaFoldDB; Q5YYX3; -.
DR   SMR; Q5YYX3; -.
DR   STRING; 247156.NFA_17720; -.
DR   EnsemblBacteria; BAD56618; BAD56618; NFA_17720.
DR   GeneID; 61132553; -.
DR   KEGG; nfa:NFA_17720; -.
DR   eggNOG; COG1799; Bacteria.
DR   HOGENOM; CLU_078499_0_0_11; -.
DR   OMA; YFGMVPL; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.150; -; 1.
DR   HAMAP; MF_01197; SepF; 1.
DR   InterPro; IPR023052; Cell_div_SepF.
DR   InterPro; IPR007561; Cell_div_SepF/SepF-rel.
DR   InterPro; IPR038594; SepF-like_sf.
DR   PANTHER; PTHR35798; PTHR35798; 1.
DR   Pfam; PF04472; SepF; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome; Septation.
FT   CHAIN           1..280
FT                   /note="Cell division protein SepF"
FT                   /id="PRO_0000334051"
FT   REGION          22..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..93
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   280 AA;  31495 MW;  72854F783651F0B7 CRC64;
     MSTLHKFKAY FGMVPLEDYE DDYVDDRAPR ASERGGARGP RPYSERAGYG ADRYGEDRYS
     ADRFGPERFG AERFGPDRFG ADRFDEDADY PEPAYKSYKS GYPVARRDDY PEDAYGEDRY
     EAPRRPTRID AAPSSGRFRA GGGAPMLRGA TRGALAVDPE AEERRLEERM RPEPVVARRP
     GIFEDGGPLS KITTLRPRDY SEARIIGERF REGNPVIMDL VELSNADAKR LVDFAAGLAF
     ALRGSFDKVA TKVFLLSPAD VDVSAEERRR IAETGFYNQK