ID   SERF2_CAPHI             Reviewed;          59 AA.
AC   A5JSS4;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=Small EDRK-rich factor 2;
GN   Name=SERF2;
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Xinong Saanen; TISSUE=Mammary gland;
RA   Han X.F., Luo J., Wu N., Matand K., Yang B.J., Wu H.J., Zhang L.J.,
RA   Wang H.B., Qi Y.;
RT   "Primary expression profile analysis and novel gene discovery of Xinong
RT   Saanen dairy goat mammary gland.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positive regulator of amyloid protein aggregation and
CC       proteotoxicity (By similarity). Induces conformational changes in
CC       amyloid proteins, such as HTT, driving them into compact formations
CC       preceding the formation of aggregates (By similarity).
CC       {ECO:0000250|UniProtKB:P84101}.
CC   -!- SIMILARITY: Belongs to the SERF family. {ECO:0000305}.
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DR   EMBL; EF564262; ABQ51189.1; -; mRNA.
DR   RefSeq; NP_001273891.1; NM_001286962.1.
DR   AlphaFoldDB; A5JSS4; -.
DR   Ensembl; ENSCHIT00000023804; ENSCHIP00000015998; ENSCHIG00000016434.
DR   GeneID; 100860778; -.
DR   KEGG; chx:100860778; -.
DR   CTD; 10169; -.
DR   GeneTree; ENSGT00940000164082; -.
DR   OMA; QRDADIM; -.
DR   OrthoDB; 1641955at2759; -.
DR   Proteomes; UP000291000; Chromosome 21.
DR   Bgee; ENSCHIG00000016434; Expressed in thymus and 17 other tissues.
DR   InterPro; IPR040211; SERF1/2.
DR   InterPro; IPR007513; Uncharacterised_SERF_N.
DR   PANTHER; PTHR13596; PTHR13596; 1.
DR   Pfam; PF04419; 4F5; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..59
FT                   /note="Small EDRK-rich factor 2"
FT                   /id="PRO_0000357057"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   59 AA;  6900 MW;  24FB33BF94FFFAE4 CRC64;
     MTRGNQRELA RQKNMKKQSD SVKGKRRDDG LSAAARKQRD SEIMQQKQKK ANEKKEEPK