ID   SERO_GALME              Reviewed;         167 AA.
AC   O76192;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Seroin;
DE   AltName: Full=Silk 23 kDa glycoprotein;
DE   Flags: Precursor;
OS   Galleria mellonella (Greater wax moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea;
OC   Pyralidae; Galleriinae; Galleria.
OX   NCBI_TaxID=7137;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 18-31.
RC   TISSUE=Silk gland;
RX   PubMed=9624126; DOI=10.1074/jbc.273.25.15423;
RA   Zurovec M., Yang C., Kodrik D., Sehnal F.;
RT   "Identification of a novel type of silk protein and regulation of its
RT   expression.";
RL   J. Biol. Chem. 273:15423-15428(1998).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Produced by both the posterior (PSG) and middle
CC       (MSG) sections of silk glands.
CC   -!- DEVELOPMENTAL STAGE: Seroin mRNA is high in the silk glands of feeding
CC       larvae, declines at ecdysis, reaches a maximum during cocoon spinning,
CC       and thereafter rapidly drops to an undetectable level.
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DR   EMBL; AF009828; AAC25171.1; -; mRNA.
DR   AlphaFoldDB; O76192; -.
DR   Proteomes; UP000504614; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Reference proteome; Repeat;
KW   Secreted; Signal; Silk protein.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000269|PubMed:9624126"
FT   CHAIN           18..167
FT                   /note="Seroin"
FT                   /id="PRO_0000022322"
FT   REPEAT          38..46
FT                   /note="1-1"
FT   REPEAT          56..64
FT                   /note="1-2"
FT   REPEAT          76..78
FT                   /note="2-1"
FT   REPEAT          79..81
FT                   /note="2-2"
FT   REPEAT          82..84
FT                   /note="2-3"
FT   REGION          145..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        146
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   167 AA;  18088 MW;  27A6ABE862774EB9 CRC64;
     MATKILIFLS FVALSSAGFV WVDDDNNSFP KLRQLYVPPL PQPPPLPNIP GLPQPPPLPQ
     PPPLFGFDFS PILPIPPIPP IPPILPTPPF INIPAPEDIK NIKPKPGQFF NGISVKSRSG
     YALDKDGNRV KTGGTAVLIN DNGEVNETIV GDNPPKFEES RKESSSN