ID   SERP2_BOVIN             Reviewed;          65 AA.
AC   Q3T073;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Stress-associated endoplasmic reticulum protein 2;
DE   AltName: Full=Ribosome-associated membrane protein RAMP4-2;
GN   Name=SERP2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May interact with target proteins during translocation into
CC       the lumen of the endoplasmic reticulum. May protect unfolded target
CC       proteins against degradation and facilitate correct glycosylation
CC       (Potential). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein.
CC       Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RAMP4 family. {ECO:0000305}.
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DR   EMBL; BC102539; AAI02540.1; -; mRNA.
DR   RefSeq; NP_001107193.1; NM_001113721.1.
DR   AlphaFoldDB; Q3T073; -.
DR   SMR; Q3T073; -.
DR   PRIDE; Q3T073; -.
DR   Ensembl; ENSBTAT00000078230; ENSBTAP00000057917; ENSBTAG00000051524.
DR   GeneID; 613627; -.
DR   KEGG; bta:613627; -.
DR   CTD; 387923; -.
DR   VEuPathDB; HostDB:ENSBTAG00000051524; -.
DR   VGNC; VGNC:106921; SERP2.
DR   GeneTree; ENSGT00940000162467; -.
DR   InParanoid; Q3T073; -.
DR   OMA; KHPVGPI; -.
DR   OrthoDB; 1605112at2759; -.
DR   Proteomes; UP000009136; Chromosome 12.
DR   Bgee; ENSBTAG00000051524; Expressed in semen and 85 other tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IBA:GO_Central.
DR   GO; GO:0006486; P:protein glycosylation; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010580; ER_stress-assoc.
DR   PANTHER; PTHR15601; PTHR15601; 1.
DR   Pfam; PF06624; RAMP4; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..65
FT                   /note="Stress-associated endoplasmic reticulum protein 2"
FT                   /id="PRO_0000274798"
FT   TOPO_DOM        1..37
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..65
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   65 AA;  7431 MW;  4CA89CEF04336C06 CRC64;
     MVAKQRIRMA NEKHSKNITQ RGNVAKTLRP QEEKYPVGPW LLALFVFVVC GSAIFQIIQS
     IRMGM