ID   SES1A_XENLA             Reviewed;         696 AA.
AC   Q6GPX2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=SEC14 domain and spectrin repeat-containing protein 1-A;
GN   Name=sestd1-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as the primary docking protein directing membrane
CC       turnover and assembly of the transient receptor potential channels
CC       trpc4 and trpc5. Binds phospholipids (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SOLO family. {ECO:0000305}.
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DR   EMBL; BC072983; AAH72983.1; -; mRNA.
DR   RefSeq; NP_001085587.1; NM_001092118.1.
DR   AlphaFoldDB; Q6GPX2; -.
DR   SMR; Q6GPX2; -.
DR   DNASU; 444013; -.
DR   GeneID; 444013; -.
DR   KEGG; xla:444013; -.
DR   CTD; 444013; -.
DR   Xenbase; XB-GENE-977662; sestd1.S.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 444013; Expressed in blastula and 19 other tissues.
DR   CDD; cd00170; SEC14; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..696
FT                   /note="SEC14 domain and spectrin repeat-containing protein
FT                   1-A"
FT                   /id="PRO_0000309498"
FT   DOMAIN          1..153
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   REPEAT          272..378
FT                   /note="Spectrin 1"
FT   REPEAT          381..494
FT                   /note="Spectrin 2"
FT   REPEAT          500..602
FT                   /note="Spectrin 3"
SQ   SEQUENCE   696 AA;  79523 MW;  4DF75E2F7CC2DA39 CRC64;
     MDTTTILPIL KKKLAFLSGG KDRRSGLILT IPLCSDQTSM DELSVTLDYL LSIPSEKCKA
     RGFTVIVDGR KSQWNVVKTV VLMLQNVVPA EVSLVCVVKP DEFWDKKVTH FCFWKEKDRL
     GFEVILVSGN KLTRYIEPSQ LTEQFGGSLT YDHMDWLNKR LVFEKFTKES TSLLDELAVI
     NNGSDKGSQD EKERSVDFNY LPSVDPETVL QTGHELLSEL QQRRFNGSDG GVSWSPMDDE
     LLAQPQVMKL LDSLREQYTR YQEVCRQRSK RTQLDEIQQK VMQVVGWLEG PGSEQLRTQW
     GIGDSFRASQ AFQQKHEEIE SQHSEWFAVY VELNQQIAAL LNAGDEEDLV ELKTLQQRLS
     DVCYRQASQL EFRQNLLQIA LEFHSVAQDL SQQLDGLLGM LCVDVAPSDG SAIQQTLKLL
     EEKLKSVDTG LQGLRDKGQG LLDQITNQAT WAYGKDVSTE NKDNVDHIQG VMEDMQLRKQ
     RCEDMVDVRR LKMLQMVQLF KCEEDAAQAV DWLNELLDAL LKTHIRLGDD SQETKILLEK
     HRKFVDVAQS TYDYGRQLLQ ATVVLCQSLR CTSRSSGDTL PKLNRVWKQF TITSEERVHR
     LEMALAFHSN AEKILQECPD LGEAVMEFEQ FDEVEAVGKS LLDRLTVPVI YPDGTEQYFG
     TPSDMAFTAE HIRERIKMVC LKKQQLLEPD ESIRES