ID   SES1B_XENLA             Reviewed;         649 AA.
AC   Q6GNM9;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=SEC14 domain and spectrin repeat-containing protein 1-B;
GN   Name=sestd1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as the primary docking protein directing membrane
CC       turnover and assembly of the transient receptor potential channels
CC       trpc4 and trpc5. Binds phospholipids (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SOLO family. {ECO:0000305}.
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DR   EMBL; BC073475; AAH73475.1; -; mRNA.
DR   RefSeq; NP_001085886.1; NM_001092417.1.
DR   AlphaFoldDB; Q6GNM9; -.
DR   SMR; Q6GNM9; -.
DR   DNASU; 444313; -.
DR   GeneID; 444313; -.
DR   KEGG; xla:444313; -.
DR   CTD; 444313; -.
DR   Xenbase; XB-GENE-17336952; sestd1.L.
DR   OrthoDB; 230255at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 444313; Expressed in heart and 19 other tissues.
DR   CDD; cd00170; SEC14; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..649
FT                   /note="SEC14 domain and spectrin repeat-containing protein
FT                   1-B"
FT                   /id="PRO_0000309499"
FT   DOMAIN          1..153
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   REPEAT          272..378
FT                   /note="Spectrin 1"
FT   REPEAT          381..494
FT                   /note="Spectrin 2"
FT   REPEAT          500..602
FT                   /note="Spectrin 3"
SQ   SEQUENCE   649 AA;  74035 MW;  3AEC9FDF4E8FB859 CRC64;
     MDATVILPIL KKKLAFLSGG KDRRSGLILT IPLCSDQTSM DELSVTLDYL LSIPSEKCKA
     RGFTVIVDGR KSQWNVVKTV VLMLQNVVPA EVSLVCVVKP DEFWDKKVTH FCFWKEKDRL
     GFEVILVSGN KLTRYIEPNQ LTEEFGGSLT YDHMDWLNKR LVFEKFTKES TSLLDELAVI
     NNGSDKGSQN EKERSVDFNY LPSVDPETVL QTGHELLSEL QQRRFNGSDG GVSWSPMDDE
     LLAQPQVMKL LDSLREQYTR YQEVCRQRSK RTQLDEIQQK VMQVVSWLEG PGSEQLRTQW
     GIGDSIRASQ ALQQKHEEIE SQHSEWFAVY VELNQQIAAL LNAGDEEDLV ELKTLQQRLS
     DVCYRQASQL EFRQNLLQIA LEFHSVSQDL SQQLDGLLGM LCADVAPTDG ATIQQTLKLL
     EEKLKSVDTG LQGLREKGQG LLDQITNQAS WAYGKDVSTE NKDNVDHIQG VMEDMQLRKQ
     RCEDMVDVRR LKMLQMVQLF KCEEDAAQAV DWLNELLDAL LKTHIRLGDD SQETKILLEK
     HRKFVDVAQS TYDYGRQLLQ ATVVLCQSLR CTSRSSGDTL PKLNRVWKQF TITSEERVQR
     LEMALAFHSN AEKILQECPD LGETVMDFEQ FDEVEAVGKS LLDRLTVPD