ID   SET5_USTMA              Reviewed;         498 AA.
AC   Q4PBP5; A0A0D1E207;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Potential protein lysine methyltransferase SET5;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 5;
GN   Name=SET5; ORFNames=UMAG_02468;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative protein lysine methyltransferase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding methyltransferase
CC       superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
CC       {ECO:0000255|PROSITE-ProRule:PRU00190}.
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DR   EMBL; CM003144; KIS69956.1; -; Genomic_DNA.
DR   RefSeq; XP_011388750.1; XM_011390448.1.
DR   AlphaFoldDB; Q4PBP5; -.
DR   STRING; 5270.UM02468P0; -.
DR   EnsemblFungi; KIS69956; KIS69956; UMAG_02468.
DR   GeneID; 23563208; -.
DR   KEGG; uma:UMAG_02468; -.
DR   VEuPathDB; FungiDB:UMAG_02468; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   HOGENOM; CLU_031650_0_0_1; -.
DR   InParanoid; Q4PBP5; -.
DR   OMA; HGGLYVL; -.
DR   OrthoDB; 1001347at2759; -.
DR   Proteomes; UP000000561; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IBA:GO_Central.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IBA:GO_Central.
DR   Gene3D; 2.170.270.10; -; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SSF82199; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Nucleus; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..498
FT                   /note="Potential protein lysine methyltransferase SET5"
FT                   /id="PRO_0000324472"
FT   DOMAIN          108..415
FT                   /note="SET"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00190"
FT   REGION          68..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  54945 MW;  F27DFB3636FD2CE3 CRC64;
     MVAPSETQIV QAVKAKLESG LTSTSDVVRE DEVRRLLATL ELEHDWQDIA VKKFISILCK
     HSLMPVSKPN DGCTSRSTSC PGGKKKKKSK TDTSIPKSFI DPTISFPAGI RGVYFDPVKG
     KGLVATRSFS KGDLLFTEDA YIPTPPPEAF DQMASGQLCA QCFLPISSAP VALAIKNCSK
     CKHRFCTTAC YKTAMATHHT LLCTGINASA KPLIELIERQ KWQSLHCVAR SLARLLMTLT
     RQYHGQANKK ADTQDSVATY GDFETVYARL SSFATVSELE RRSRNPGWTT EKASFESILV
     EAHTALCNAL DPYSSTRNAN LEPFHVSADY LDSTRKPLIK DLFCLATFMK LVGRANINME
     KFGGLYSLHS FLNHSCSPNL EIRHVPERAI LSSMKVAAIA LCDIHPDDEL VISYIDPNTS
     LARRQLLLYR DYCFGPCTCD KCTTQLGALG LVYDPAKHAV KAFLDSVAHK TRPDPDHTLP
     PTSQDSTLED QLRASLGF