ID   SETD9_PONAB             Reviewed;         273 AA.
AC   Q5RBW0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=SET domain-containing protein 9;
DE            EC=2.1.1.-;
GN   Name=SETD9;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding methyltransferase
CC       superfamily. {ECO:0000255|PROSITE-ProRule:PRU00190}.
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DR   EMBL; CR858523; CAH90750.1; -; mRNA.
DR   RefSeq; NP_001125419.1; NM_001131947.1.
DR   AlphaFoldDB; Q5RBW0; -.
DR   STRING; 9601.ENSPPYP00000017295; -.
DR   Ensembl; ENSPPYT00000034988; ENSPPYP00000028524; ENSPPYG00000015479.
DR   GeneID; 100172326; -.
DR   KEGG; pon:100172326; -.
DR   CTD; 133383; -.
DR   eggNOG; ENOG502QVIC; Eukaryota.
DR   GeneTree; ENSGT00390000001437; -.
DR   InParanoid; Q5RBW0; -.
DR   Proteomes; UP000001595; Chromosome 5.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.270.10; -; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR040415; SETD9.
DR   PANTHER; PTHR33524; PTHR33524; 1.
DR   SUPFAM; SSF82199; SSF82199; 1.
DR   PROSITE; PS50280; SET; 1.
PE   2: Evidence at transcript level;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..273
FT                   /note="SET domain-containing protein 9"
FT                   /id="PRO_0000300497"
FT   DOMAIN          96..269
FT                   /note="SET"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00190"
FT   BINDING         268
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00190"
SQ   SEQUENCE   273 AA;  30548 MW;  2BDCA695E41D3586 CRC64;
     MVGFGLGTLR YVPEESKDKV TSDEDVLGTL LKVFQALFLN DFNKQSEILT MLPESVKSKY
     QDLLAVEHQG VKLLENRHQQ QSTFKPEEIL YKTLGFSVAQ ATSSLISAGK GVFVTKGLVP
     KGAVVSMYPG TVYQKYEPIF FQSIGNPFIF RCLDGVLIDG NDKGISKVVY RSCNGRDRLG
     PLKMSDSTWL TSEIHNPLAV GQYVNNCSND RAANVCYQEF DVPAVFPIEL KQYLPNIAYS
     YDKHSPLRCV VLVALRDINQ GEELFSNYYT IVS