SF3B6_ARATH
ID SF3B6_ARATH Reviewed; 124 AA.
AC Q9FMP4;
DT 16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Splicing factor 3B subunit 6-like protein;
DE AltName: Full=Pre-mRNA branch site p14-like protein;
GN OrderedLocusNames=At5g12190; ORFNames=MXC9_15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be necessary for the splicing of pre-mRNA. {ECO:0000250}.
CC -!- INTERACTION:
CC Q9FMP4; Q9FDW1: MYB44; NbExp=3; IntAct=EBI-4459215, EBI-15192813;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; AB007727; BAB10037.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91772.1; -; Genomic_DNA.
DR EMBL; BT002829; AAO22648.1; -; mRNA.
DR EMBL; BT004430; AAO42424.1; -; mRNA.
DR EMBL; AY088716; AAM67034.1; -; mRNA.
DR RefSeq; NP_196780.1; NM_121257.3.
DR AlphaFoldDB; Q9FMP4; -.
DR SMR; Q9FMP4; -.
DR BioGRID; 16370; 4.
DR IntAct; Q9FMP4; 4.
DR STRING; 3702.AT5G12190.1; -.
DR PaxDb; Q9FMP4; -.
DR PRIDE; Q9FMP4; -.
DR ProteomicsDB; 232676; -.
DR EnsemblPlants; AT5G12190.1; AT5G12190.1; AT5G12190.
DR GeneID; 831092; -.
DR Gramene; AT5G12190.1; AT5G12190.1; AT5G12190.
DR KEGG; ath:AT5G12190; -.
DR Araport; AT5G12190; -.
DR TAIR; locus:2177033; AT5G12190.
DR eggNOG; KOG0114; Eukaryota.
DR HOGENOM; CLU_012062_25_2_1; -.
DR InParanoid; Q9FMP4; -.
DR OMA; GYNFMDR; -.
DR OrthoDB; 1603846at2759; -.
DR PhylomeDB; Q9FMP4; -.
DR PRO; PR:Q9FMP4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FMP4; baseline and differential.
DR Genevisible; Q9FMP4; AT.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd12241; RRM_SF3B14; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034150; SF3B6_RRM.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 1: Evidence at protein level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..124
FT /note="Splicing factor 3B subunit 6-like protein"
FT /id="PRO_0000081729"
FT DOMAIN 19..94
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 16..29
FT /note="Interaction with pre-mRNA branch site"
FT /evidence="ECO:0000250"
SQ SEQUENCE 124 AA; 14383 MW; 1C779255D02BFB3F CRC64;
MTTISLRKSN TRLPPEVNRV LYVRNLPFNI TSEEMYDIFG KYGAIRQIRI GCDKATKGTA
FVVYEDIYDA KNAVDHLSGF NVANRYLIVL YYQHAKMSKK FDQKKSEDEI TKLQEKYGVS
TKDK