ID   SF3B6_CAEEL             Reviewed;         138 AA.
AC   Q8ITY4;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Splicing factor 3B subunit 6-like protein;
DE   AltName: Full=Pre-mRNA branch site p14-like protein;
GN   ORFNames=C50D2.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Necessary for the splicing of pre-mRNA.
CC       {ECO:0000250|UniProtKB:Q9Y3B4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; FO080633; CCD65337.1; -; Genomic_DNA.
DR   RefSeq; NP_493659.3; NM_061258.4.
DR   AlphaFoldDB; Q8ITY4; -.
DR   SMR; Q8ITY4; -.
DR   BioGRID; 38774; 11.
DR   STRING; 6239.C50D2.5; -.
DR   EPD; Q8ITY4; -.
DR   PaxDb; Q8ITY4; -.
DR   PeptideAtlas; Q8ITY4; -.
DR   EnsemblMetazoa; C50D2.5.1; C50D2.5.1; WBGene00016808.
DR   GeneID; 173394; -.
DR   KEGG; cel:CELE_C50D2.5; -.
DR   UCSC; C50D2.5; c. elegans.
DR   CTD; 173394; -.
DR   WormBase; C50D2.5; CE38492; WBGene00016808; -.
DR   eggNOG; KOG0114; Eukaryota.
DR   GeneTree; ENSGT00390000005908; -.
DR   HOGENOM; CLU_012062_25_2_1; -.
DR   InParanoid; Q8ITY4; -.
DR   OMA; QKRNNVR; -.
DR   OrthoDB; 1603846at2759; -.
DR   PhylomeDB; Q8ITY4; -.
DR   Reactome; R-CEL-72163; mRNA Splicing - Major Pathway.
DR   Reactome; R-CEL-72165; mRNA Splicing - Minor Pathway.
DR   PRO; PR:Q8ITY4; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00016808; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd12241; RRM_SF3B14; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034150; SF3B6_RRM.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..138
FT                   /note="Splicing factor 3B subunit 6-like protein"
FT                   /id="PRO_0000081727"
FT   DOMAIN          19..94
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          16..29
FT                   /note="Interaction with pre-mRNA branch site"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   138 AA;  16006 MW;  3224CFAF15FC55D6 CRC64;
     MAMANRQNRG AKLPPEVNRI LYIKNLPYKI TTEEMYEIFG KFGAVRQIRV GNTAETRGTA
     FVVYEDIFDA KTACEHLSGY NVSNRYLVVL YYQATKAWKR MDTEKARTKL EDIKERYGIG
     GDIDKEKEKL GLFTPRRI