ID   SFH11_ARATH             Reviewed;         376 AA.
AC   F4JYJ3; Q9FGK6;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Phosphatidylinositol/phosphatidylcholine transfer protein SFH11;
DE   AltName: Full=Protein SEC FOURTEEN HOMOLOGS 11;
DE            Short=AtSFH11;
GN   Name=SFH11; OrderedLocusNames=At5g47510; ORFNames=MNJ7.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15728190; DOI=10.1083/jcb.200412074;
RA   Vincent P., Chua M., Nogue F., Fairbrother A., Mekeel H., Xu Y., Allen N.,
RA   Bibikova T.N., Gilroy S., Bankaitis V.A.;
RT   "A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes
RT   membrane growth of Arabidopsis thaliana root hairs.";
RL   J. Cell Biol. 168:801-812(2005).
RN   [4]
RP   REVIEW.
RX   PubMed=17051233; DOI=10.1038/nchembio835;
RA   Ile K.E., Schaaf G., Bankaitis V.A.;
RT   "Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid
RT   signaling.";
RL   Nat. Chem. Biol. 2:576-583(2006).
CC   -!- FUNCTION: Required for transport of secretory proteins from the Golgi
CC       complex. Catalyzes the transfer of phosphatidylinositol and
CC       phosphatidylcholine between membranes in vitro (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SFH family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB09077.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB025628; BAB09077.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED95527.1; -; Genomic_DNA.
DR   RefSeq; NP_199562.2; NM_124124.3.
DR   AlphaFoldDB; F4JYJ3; -.
DR   SMR; F4JYJ3; -.
DR   STRING; 3702.AT5G47510.1; -.
DR   PaxDb; F4JYJ3; -.
DR   PRIDE; F4JYJ3; -.
DR   ProteomicsDB; 234553; -.
DR   EnsemblPlants; AT5G47510.1; AT5G47510.1; AT5G47510.
DR   GeneID; 834801; -.
DR   Gramene; AT5G47510.1; AT5G47510.1; AT5G47510.
DR   KEGG; ath:AT5G47510; -.
DR   Araport; AT5G47510; -.
DR   TAIR; locus:2169038; AT5G47510.
DR   eggNOG; KOG1471; Eukaryota.
DR   HOGENOM; CLU_014001_6_1_1; -.
DR   InParanoid; F4JYJ3; -.
DR   PRO; PR:F4JYJ3; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; F4JYJ3; baseline and differential.
DR   Genevisible; F4JYJ3; AT.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR011074; CRAL/TRIO_N_dom.
DR   InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR   Pfam; PF00650; CRAL_TRIO; 1.
DR   SMART; SM01100; CRAL_TRIO_N; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF46938; SSF46938; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Coiled coil; Golgi apparatus; Membrane; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..376
FT                   /note="Phosphatidylinositol/phosphatidylcholine transfer
FT                   protein SFH11"
FT                   /id="PRO_0000423471"
FT   DOMAIN          92..266
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          323..357
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   376 AA;  42935 MW;  B9813B434620A97B CRC64;
     MQETDRDIHI SDGTMNKEEQ SPNNEEMVEA FRNLLLLHGH LPDKHGDHNT LRRFLKMRDF
     DLEKSKEAFL NYMKWRVDYK VDLISQKFKF EEYGEVKKHY PHGFHKVDKT GRPIYIERLG
     MTDLNAFLKA TTIERYVNYH IKEQEKTMSL RYPACSIASD KHVSSTTTIL DVSGVGMSNF
     SKPARSLFME IQKIDSNYYP ETLHRLFVVN ASSGFRMLWL ALKTFLDART LAKVQVLGPN
     YLGELLEAIE PSNLPTFLGG NCTCSDHGGC LFSDEGPWND PGIKEKIEEP STIEDAHSET
     MDKVSENAPA NQKESLGEVM ITMEKYAALK TAVKDSQKRI EMLEISLHET KKVLNGLAEI
     IEAIQPNQPI TKCKPV