SFH13_ARATH
ID SFH13_ARATH Reviewed; 625 AA.
AC Q501H5; Q9LFZ9;
DT 18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Phosphatidylinositol/phosphatidylcholine transfer protein SFH13;
DE AltName: Full=Protein SEC FOURTEEN HOMOLOGS 13;
DE Short=AtSFH13;
GN Name=SFH13; OrderedLocusNames=At1g55690; ORFNames=F20N2.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=15728190; DOI=10.1083/jcb.200412074;
RA Vincent P., Chua M., Nogue F., Fairbrother A., Mekeel H., Xu Y., Allen N.,
RA Bibikova T.N., Gilroy S., Bankaitis V.A.;
RT "A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes
RT membrane growth of Arabidopsis thaliana root hairs.";
RL J. Cell Biol. 168:801-812(2005).
RN [6]
RP REVIEW.
RX PubMed=17051233; DOI=10.1038/nchembio835;
RA Ile K.E., Schaaf G., Bankaitis V.A.;
RT "Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid
RT signaling.";
RL Nat. Chem. Biol. 2:576-583(2006).
CC -!- FUNCTION: Required for transport of secretory proteins from the Golgi
CC complex. Catalyzes the transfer of phosphatidylinositol and
CC phosphatidylcholine between membranes in vitro (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q501H5-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the SFH family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79506.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002328; AAF79506.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33284.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33286.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61121.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61122.1; -; Genomic_DNA.
DR EMBL; BT021992; AAY25404.1; -; mRNA.
DR EMBL; BT046119; ACI46507.1; -; mRNA.
DR RefSeq; NP_001323358.1; NM_001333723.1. [Q501H5-1]
DR RefSeq; NP_001323359.1; NM_001333722.1. [Q501H5-1]
DR RefSeq; NP_849815.1; NM_179484.3. [Q501H5-1]
DR RefSeq; NP_849816.1; NM_179485.2. [Q501H5-1]
DR AlphaFoldDB; Q501H5; -.
DR SMR; Q501H5; -.
DR STRING; 3702.AT1G55690.1; -.
DR PaxDb; Q501H5; -.
DR PRIDE; Q501H5; -.
DR ProteomicsDB; 232975; -. [Q501H5-1]
DR EnsemblPlants; AT1G55690.1; AT1G55690.1; AT1G55690. [Q501H5-1]
DR EnsemblPlants; AT1G55690.2; AT1G55690.2; AT1G55690. [Q501H5-1]
DR EnsemblPlants; AT1G55690.4; AT1G55690.4; AT1G55690. [Q501H5-1]
DR EnsemblPlants; AT1G55690.5; AT1G55690.5; AT1G55690. [Q501H5-1]
DR GeneID; 842018; -.
DR Gramene; AT1G55690.1; AT1G55690.1; AT1G55690. [Q501H5-1]
DR Gramene; AT1G55690.2; AT1G55690.2; AT1G55690. [Q501H5-1]
DR Gramene; AT1G55690.4; AT1G55690.4; AT1G55690. [Q501H5-1]
DR Gramene; AT1G55690.5; AT1G55690.5; AT1G55690. [Q501H5-1]
DR KEGG; ath:AT1G55690; -.
DR Araport; AT1G55690; -.
DR TAIR; locus:2020492; AT1G55690.
DR eggNOG; KOG1471; Eukaryota.
DR HOGENOM; CLU_014001_11_0_1; -.
DR InParanoid; Q501H5; -.
DR OMA; HNDYHML; -.
DR OrthoDB; 1133487at2759; -.
DR PhylomeDB; Q501H5; -.
DR PRO; PR:Q501H5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q501H5; baseline and differential.
DR Genevisible; Q501H5; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; -; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF46938; SSF46938; 1.
DR SUPFAM; SSF52087; SSF52087; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Cell membrane; Golgi apparatus; Membrane;
KW Protein transport; Reference proteome; Transport.
FT CHAIN 1..625
FT /note="Phosphatidylinositol/phosphatidylcholine transfer
FT protein SFH13"
FT /id="PRO_0000423473"
FT DOMAIN 143..318
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
SQ SEQUENCE 625 AA; 72034 MW; 4AF264A2E5DFBC96 CRC64;
MSGVEEISTL DEFRERRSDF EISEDERRRS KIGNLKKKAI NASTKFTHSL KKRGKRKIDY
RVPAVSIEDV RDEKEESVVL EFRRKLLERD LLPPRHDEYH TLLRFLKARD LNIEKTTQLW
EEMLRWRKEY GTDTILEDFD FEELEEVLQY YPQGYHGVDK EGRPVYIERL GKAHPSKLMR
ITTIDRYLKY HVQEFERALQ EKFPACSIAA KRRICSTTTI LDVQGLGIKN FTPTAANLVA
AMSKIDNSYY PETLHRMYIV NAGTGFKKML WPAAQKFLDA KTIAKIHVLE PKSLFKLHEV
IDSSQLPEFL GGSCSCFGDG GGCLRSNKGP WNDPEIMKLI YHGESSLFRQ STRKLTDPHY
SSSYISIHPS KAIQAETSAA ESISCSDVPS SPTGRLCSAS SHVNSAYEEA RASDVNGYYS
CDDKFAIPDK ATNRKGQERQ SQYQMRELNA TTIGLKCETS SPGAPIIRWL HDLRVMIDKI
KCENLAKRLL SLMLKLAAVF RYTPLELLRS QTTVSPSSLT EDDSRCSLIS PPPREPTMKD
RILPCLERIQ KLEKSYEDIR NKPVAIPVEK ERMLMDSLDR IKSVEFDLDK TKRLLHATVM
KQMEITEMLQ NIRDSQLHRR RRLFC
