SFH9_ARATH
ID SFH9_ARATH Reviewed; 579 AA.
AC F4J7S8; Q9LRX7;
DT 18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Phosphatidylinositol/phosphatidylcholine transfer protein SFH9;
DE AltName: Full=Protein SEC FOURTEEN HOMOLOGS 9;
DE Short=AtSFH9;
GN Name=SFH9; OrderedLocusNames=At3g24840; ORFNames=K7P8.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=15728190; DOI=10.1083/jcb.200412074;
RA Vincent P., Chua M., Nogue F., Fairbrother A., Mekeel H., Xu Y., Allen N.,
RA Bibikova T.N., Gilroy S., Bankaitis V.A.;
RT "A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes
RT membrane growth of Arabidopsis thaliana root hairs.";
RL J. Cell Biol. 168:801-812(2005).
RN [5]
RP REVIEW.
RX PubMed=17051233; DOI=10.1038/nchembio835;
RA Ile K.E., Schaaf G., Bankaitis V.A.;
RT "Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid
RT signaling.";
RL Nat. Chem. Biol. 2:576-583(2006).
CC -!- FUNCTION: Required for transport of secretory proteins from the Golgi
CC complex. Catalyzes the transfer of phosphatidylinositol and
CC phosphatidylcholine between membranes in vitro (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SFH family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02894.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BX822701; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB028609; BAB02894.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76952.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65902.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65904.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65906.1; -; Genomic_DNA.
DR EMBL; BX822701; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001327839.1; NM_001338710.1.
DR RefSeq; NP_001327841.1; NM_001338712.1.
DR RefSeq; NP_001327843.1; NM_001338714.1.
DR RefSeq; NP_189128.2; NM_113396.6.
DR AlphaFoldDB; F4J7S8; -.
DR SMR; F4J7S8; -.
DR STRING; 3702.AT3G24840.1; -.
DR iPTMnet; F4J7S8; -.
DR PaxDb; F4J7S8; -.
DR PRIDE; F4J7S8; -.
DR ProteomicsDB; 232577; -.
DR EnsemblPlants; AT3G24840.1; AT3G24840.1; AT3G24840.
DR EnsemblPlants; AT3G24840.2; AT3G24840.2; AT3G24840.
DR EnsemblPlants; AT3G24840.4; AT3G24840.4; AT3G24840.
DR EnsemblPlants; AT3G24840.6; AT3G24840.6; AT3G24840.
DR GeneID; 822082; -.
DR Gramene; AT3G24840.1; AT3G24840.1; AT3G24840.
DR Gramene; AT3G24840.2; AT3G24840.2; AT3G24840.
DR Gramene; AT3G24840.4; AT3G24840.4; AT3G24840.
DR Gramene; AT3G24840.6; AT3G24840.6; AT3G24840.
DR KEGG; ath:AT3G24840; -.
DR Araport; AT3G24840; -.
DR TAIR; locus:2087293; AT3G24840.
DR eggNOG; KOG1471; Eukaryota.
DR HOGENOM; CLU_014001_11_1_1; -.
DR InParanoid; F4J7S8; -.
DR PRO; PR:F4J7S8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; F4J7S8; baseline and differential.
DR Genevisible; F4J7S8; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; -; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF46938; SSF46938; 1.
DR SUPFAM; SSF52087; SSF52087; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Coiled coil; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..579
FT /note="Phosphatidylinositol/phosphatidylcholine transfer
FT protein SFH9"
FT /id="PRO_0000423469"
FT DOMAIN 145..319
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT REGION 372..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 512..539
FT /evidence="ECO:0000255"
FT COMPBIAS 377..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 66625 MW; 35DE74E1C019B806 CRC64;
MPALGEILLV PETDKGKSKD YIEVSEDEKI TRTRSRSLKK KAIKASNKLT HSLRKRGKRV
ADQYAPIVIE DVRDEEEEKA VNVFRKALVS LDLLPPRHDD YHTMLRFLKA RRFDLEKTVQ
MWEEMLKWRK ENGVDTIIQD FVYDEYEEVQ QYYPHGYHGV DREGRPVYIE RLGKIDPGKL
MKVTTLERFL RYHVQGFEKT FSEKFPACSI AAKRHINSST TIIDVHGVSW MSFRKLAQDL
VMRMQKIDGD NYPETLNQMY IINAGNGFKL VWNTVKGFLD PKTTSKIHVL GNKYRSHLLE
IIDPSELPEF LGGNCKCAHE GGCMRFNKGP WNDPEIMKLV RSRDAMYKPK EMGLLENGEV
AKLFSLRHVN TDMSSPDGGH VRERESHPEH DKRAQLSNQA EAVGVGRMEQ SDSTSPLPNN
LAVERSLTTS LQKVASFLAR FILQLLGSLC LMFRILGRLV NKQPENQLRP ELSVSVSQQQ
VPPPQVHPCW LRLQNLETMV TVLCDKPSSI PQEKEDILRD SLDRIKSIEQ DLQKTKKALF
LTASKQIELA ECFENLKESS STGMRSCWPR HCRNFQAET
