ID   SFI1_CALJA              Reviewed;        1235 AA.
AC   B0KWR6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Protein SFI1 homolog;
GN   Name=SFI1;
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Antonellis A., Ayele K., Benjamin B., Blakesley R.W., Boakye A.,
RA   Bouffard G.G., Brinkley C., Brooks S., Chu G., Coleman H., Engle J.,
RA   Gestole M., Greene A., Guan X., Gupta J., Haghighi P., Han J., Hansen N.,
RA   Ho S.-L., Hu P., Hunter G., Hurle B., Idol J.R., Kwong P., Laric P.,
RA   Larson S., Lee-Lin S.-Q., Legaspi R., Madden M., Maduro Q.L., Maduro V.B.,
RA   Margulies E.H., Masiello C., Maskeri B., McDowell J., Mojidi H.A.,
RA   Mullikin J.C., Oestreicher J.S., Park M., Portnoy M.E., Prasad A., Puri O.,
RA   Reddix-Dugue N., Schandler K., Schueler M.G., Sison C., Stantripop S.,
RA   Stephen E., Taye A., Thomas J.W., Thomas P.J., Tsipouri V., Ung L.,
RA   Vogt J.L., Wetherby K.D., Young A., Green E.D.;
RT   "NISC comparative sequencing initiative.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the dynamic structure of centrosome-
CC       associated contractile fibers via its interaction with CETN2.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with CETN2 (via C-terminus). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome, centriole {ECO:0000250}. Note=Localized close to
CC       the centriole. {ECO:0000250}.
CC   -!- DOMAIN: CETN2-binding regions contains a conserved Trp residue in their
CC       C-terminal ends, which seems critical for interaction with CETN2.
CC   -!- SIMILARITY: Belongs to the SFI1 family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-17 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; DP000586; ABZ10459.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0KWR6; -.
DR   SMR; B0KWR6; -.
DR   STRING; 9483.ENSCJAP00000043459; -.
DR   PRIDE; B0KWR6; -.
DR   eggNOG; KOG4775; Eukaryota.
DR   InParanoid; B0KWR6; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0019902; F:phosphatase binding; ISS:UniProtKB.
DR   InterPro; IPR030516; SFI1.
DR   PANTHER; PTHR22028:SF4; PTHR22028:SF4; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome; Repeat.
FT   CHAIN           1..1235
FT                   /note="Protein SFI1 homolog"
FT                   /id="PRO_0000334620"
FT   REPEAT          131..163
FT                   /note="HAT 1"
FT   REPEAT          165..194
FT                   /note="HAT 2"
FT   REPEAT          263..295
FT                   /note="HAT 3"
FT   REPEAT          327..361
FT                   /note="HAT 4"
FT   REPEAT          392..424
FT                   /note="HAT 5"
FT   REPEAT          1141..1173
FT                   /note="HAT 6"
FT   REGION          104..123
FT                   /note="Interaction with CETN2"
FT                   /evidence="ECO:0000250"
FT   REGION          468..487
FT                   /note="Interaction with CETN2"
FT                   /evidence="ECO:0000250"
FT   REGION          634..653
FT                   /note="Interaction with CETN2"
FT                   /evidence="ECO:0000250"
FT   REGION          1010..1075
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1235 AA;  146795 MW;  BCEEB1688C9ABAD0 CRC64;
     MSSRWLNFHE KMIKQRMEKK VDSRYFRDGA VKKPYSPKTL SNKKSSASLG IRRELPSTSH
     LVQYRGTHAC TRQGRLRELH IRCVARKFLY LWIRMTFGRV FPSKARFYYE QQLLRKIFGE
     WKEEWWVFHH EWKLCVRADC HYRYYLYNLM FQTWKTYVHQ QQEMRSKYIR AEVHDAKQKM
     RQAWKSWLIY VVFRRTKLQM QTMALEFRQR SILRVWWSMW RQRLGQIRVS RALHASAVKH
     RSLSLQLQAW SQWWEQLLYA QKEKQKVASA VKHRQHWQKR RFLKAWLAYL QIRRVKRQQN
     EMAERLHHVT MLQIHFCNWQ QAWERRESLH AHQAQVEKLA RKMALRCTFT HWKHYMLLCA
     EEAAQCEMAE EHHRHRRLYF CFRALKDNVA YTHLQQIRRN LAYQQRGITL LHRFWNLWWS
     QIEKKKEREQ LPLLHAAWDH HRMALLCKCV KWWLQYTQKR RYKQLLQARA DGHFQQRALP
     AAFHTWNRLW RSHQQENVLS ARATHFHREK VEKQVFSIWW QKMVQHRENR LAERMAILHA
     ERQLLHRSWF TWHQQAAAHH QEQEWQTVAR AYHRCRRLRK AFCLWRESAR GLRTERMGRV
     QAAEFNAAQL LRWAWSQWRE CLALRGAERR KLMRAELHHQ HTVLLRALQA WVTYQGRVQS
     ILQEVAAKES QHNRQLLRGV LRRWKENTMA RMNEAKKTFQ ASTHYRKTIC SKVLVQWREI
     ASVQIYYRQQ EDHAIWEARK VLARGCLRTW FQRWRDCSRR SAQQRLQLER AAQHHHRQLL
     LEGLARWKTH HLGCVRKRLL HRQSTQLLAQ RLSQTCFHQW RQQLAARRQE QQASVRALWF
     WAFSLQAKVW ATWLAFVLER RRKKARMQQA FQAYQGQLLQ EGAMRLLRFA AGMKASRQQL
     QAQQQVQAAH SLHRAVRHCA TLWKQKVLGR GREPQPLAPI TPSRKVTFEG TLLNRIAAGA
     GDATLETKRP QAPWSQGALG RLAAREPHAL EFNTAHSSRK QPRRPHFLLE PAQGQRPQKL
     QEHGLGMAEP AGPSLTHPFL AEAPTAPVPH SPLPRALSSA PGPKQAPTAS TGPELLLLPP
     SSFMPHGAAA PARVSAQPAT PRHMPQVPPS LASVPGPHPL LPGDFSGIGA GPRLSTAGCL
     DLEAELEGIQ QQLLHYQTTK QNLWSCQRQA SSLRRWLELN REEPGPEDQE VEQQVQKELE
     EVELQIQQLA EELQAQRQPT GACIARIQAL RQALG