ID   SFNR_PSEPF              Reviewed;         367 AA.
AC   Q3K999;
DT   28-MAR-2018, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Sigma54-dependent transcriptional regulator SfnR {ECO:0000250|UniProtKB:Q845S7};
GN   Name=sfnR {ECO:0000250|UniProtKB:Q845S7};
GN   OrderedLocusNames=Pfl01_3918 {ECO:0000312|EMBL:ABA75655.1};
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1 {ECO:0000312|EMBL:ABA75655.1,
RC   ECO:0000312|Proteomes:UP000002704};
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Involved in the dimethyl sulfide degradation pathway.
CC       Activates the expression of sfnG and sfnF.
CC       {ECO:0000250|UniProtKB:Q845S7}.
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DR   EMBL; CP000094; ABA75655.1; -; Genomic_DNA.
DR   RefSeq; WP_011335233.1; NC_007492.2.
DR   AlphaFoldDB; Q3K999; -.
DR   SMR; Q3K999; -.
DR   STRING; 205922.Pfl01_3918; -.
DR   EnsemblBacteria; ABA75655; ABA75655; Pfl01_3918.
DR   KEGG; pfo:Pfl01_3918; -.
DR   eggNOG; COG3829; Bacteria.
DR   HOGENOM; CLU_000445_0_7_6; -.
DR   OMA; DLPMAIQ; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   3: Inferred from homology;
KW   Activator; ATP-binding; DNA-binding; Nucleotide-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..367
FT                   /note="Sigma54-dependent transcriptional regulator SfnR"
FT                   /id="PRO_0000443544"
FT   DOMAIN          21..250
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         49..56
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         112..121
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ   SEQUENCE   367 AA;  41035 MW;  75844390AC2C88CE CRC64;
     MQLLTLPPSP ALATSIRATA QVFEDPKSQA LLAHLQQVAP SEASVLIIGE TGTGKELVAR
     HIHNLSNRRN RPFIAVNCGA FSESLVEAEL FGHEKGAFTG ALSAKAGWFE EADGGTLFLD
     EIGDLPMAIQ VKLLRVLQER EVVRLGSRKS IPIDVRVLAA TNVQLEKAIN AGHFREDLYY
     RLNVVNLELS PLRDRPGDIL PLTRHFIEAY SQRLGYGRVT ISPGAEHKLR GYSWPGNIRE
     LENVIHHTLL ICRNGVIERD DLRLSNLRID RPDDQHATAD DSPEALLERA FQKLFEQQAG
     ALHEKVEDAL LRSAYRFCHY NQVHTASLLG LSRNVTRTRL IKIGELAVNK RRPTENLQGE
     RLIQLSI