SFSA_ECOBW
ID SFSA_ECOBW Reviewed; 234 AA.
AC C4ZRN9;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Sugar fermentation stimulation protein A {ECO:0000255|HAMAP-Rule:MF_00095};
GN Name=sfsA {ECO:0000255|HAMAP-Rule:MF_00095}; OrderedLocusNames=BWG_0139;
OS Escherichia coli (strain K12 / MC4100 / BW2952).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=595496;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MC4100 / BW2952;
RX PubMed=19376874; DOI=10.1128/jb.00118-09;
RA Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA Wang L.;
RT "Genomic sequencing reveals regulatory mutations and recombinational events
RT in the widely used MC4100 lineage of Escherichia coli K-12.";
RL J. Bacteriol. 191:4025-4029(2009).
CC -!- FUNCTION: Binds to DNA non-specifically. Could be a regulatory factor
CC involved in maltose metabolism. {ECO:0000255|HAMAP-Rule:MF_00095}.
CC -!- SIMILARITY: Belongs to the SfsA family. {ECO:0000255|HAMAP-
CC Rule:MF_00095}.
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DR EMBL; CP001396; ACR64252.1; -; Genomic_DNA.
DR RefSeq; WP_000396036.1; NC_012759.1.
DR AlphaFoldDB; C4ZRN9; -.
DR SMR; C4ZRN9; -.
DR KEGG; ebw:BWG_0139; -.
DR HOGENOM; CLU_052299_2_0_6; -.
DR OMA; VTAHCPN; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR HAMAP; MF_00095; SfsA; 1.
DR InterPro; IPR005224; SfsA.
DR InterPro; IPR040452; SfsA_C.
DR InterPro; IPR041465; SfsA_N.
DR PANTHER; PTHR30545; PTHR30545; 1.
DR Pfam; PF03749; SfsA; 1.
DR Pfam; PF17746; SfsA_N; 1.
DR TIGRFAMs; TIGR00230; sfsA; 1.
PE 3: Inferred from homology;
KW DNA-binding.
FT CHAIN 1..234
FT /note="Sugar fermentation stimulation protein A"
FT /id="PRO_1000202720"
FT DNA_BIND 201..220
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00095"
SQ SEQUENCE 234 AA; 26229 MW; 8AF528989FE78DCD CRC64;
MEFSPPLQRA TLIQRYKRFL ADVITPDGRE LTLHCPNTGA MTGCATPGDT VWYSTSDNTK
RKYPHTWELT QSQSGAFICV NTLWANRLTK EAILNESISE LSGYSSLKSE VKYGAERSRI
DFMLQADSRP DCYIEVKSVT LAENEQGYFP DAVTERGQKH LRELMSVAAE GQRAVIFFAV
LHSAITRFSP ARHIDEKYAQ LLSEAQQRGV EILAYKAEIS AEGMALKKSL PVTL