SFSA_SALTI
ID SFSA_SALTI Reviewed; 234 AA.
AC Q8Z9C1;
DT 13-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Sugar fermentation stimulation protein A {ECO:0000255|HAMAP-Rule:MF_00095};
GN Name=sfsA {ECO:0000255|HAMAP-Rule:MF_00095};
GN OrderedLocusNames=STY0212, t0195;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Binds to DNA non-specifically. Could be a regulatory factor
CC involved in maltose metabolism. {ECO:0000255|HAMAP-Rule:MF_00095}.
CC -!- SIMILARITY: Belongs to the SfsA family. {ECO:0000255|HAMAP-
CC Rule:MF_00095}.
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DR EMBL; AL513382; CAD01348.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO67927.1; -; Genomic_DNA.
DR RefSeq; NP_454803.1; NC_003198.1.
DR RefSeq; WP_000899414.1; NZ_WSUR01000009.1.
DR AlphaFoldDB; Q8Z9C1; -.
DR SMR; Q8Z9C1; -.
DR STRING; 220341.16501476; -.
DR EnsemblBacteria; AAO67927; AAO67927; t0195.
DR KEGG; stt:t0195; -.
DR KEGG; sty:STY0212; -.
DR PATRIC; fig|220341.7.peg.215; -.
DR eggNOG; COG1489; Bacteria.
DR HOGENOM; CLU_052299_2_0_6; -.
DR OMA; VTAHCPN; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR HAMAP; MF_00095; SfsA; 1.
DR InterPro; IPR005224; SfsA.
DR InterPro; IPR040452; SfsA_C.
DR InterPro; IPR041465; SfsA_N.
DR PANTHER; PTHR30545; PTHR30545; 1.
DR Pfam; PF03749; SfsA; 1.
DR Pfam; PF17746; SfsA_N; 1.
DR TIGRFAMs; TIGR00230; sfsA; 1.
PE 3: Inferred from homology;
KW DNA-binding.
FT CHAIN 1..234
FT /note="Sugar fermentation stimulation protein A"
FT /id="PRO_0000152303"
FT DNA_BIND 201..220
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00095"
SQ SEQUENCE 234 AA; 26119 MW; ECC8C5EB46B60EC0 CRC64;
MLFSPPLQRA TLIQRYKRFL ADVITPDGTT LTLHCPNTGA MTGCATPGDT VWYSTSENTK
RKYPHTWELT ETQSGAFICV NTLRANQLTK EAIQENRLPA LAGYNILNSE VKYGAERSRI
DFMLQADFRP DCYIEVKSVT LAEKENGYFP DAITERGQKH LRELMGVAAA GHRAVVVFAV
LHSAITRFSP ARHIDIKYAQ LLSEAQNKGV EVLAYKAELS ATKMELNEPV PITL