ID   SFSB_SHIFL              Reviewed;          92 AA.
AC   P0ACH4; P18837;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Sugar fermentation stimulation protein B;
DE   AltName: Full=Ner-like protein;
GN   Name=sfsB; OrderedLocusNames=SF3228, S3446;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: This protein is involved in positive regulation of the
CC       metabolism of sugars. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ner transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005674; AAN44694.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18508.1; -; Genomic_DNA.
DR   RefSeq; NP_708987.1; NC_004337.2.
DR   RefSeq; WP_000445413.1; NZ_WPGW01000004.1.
DR   AlphaFoldDB; P0ACH4; -.
DR   SMR; P0ACH4; -.
DR   STRING; 198214.SF3228; -.
DR   PRIDE; P0ACH4; -.
DR   EnsemblBacteria; AAN44694; AAN44694; SF3228.
DR   EnsemblBacteria; AAP18508; AAP18508; S3446.
DR   GeneID; 1027129; -.
DR   GeneID; 67415978; -.
DR   KEGG; sfl:SF3228; -.
DR   KEGG; sfx:S3446; -.
DR   PATRIC; fig|198214.7.peg.3829; -.
DR   HOGENOM; CLU_162005_0_1_6; -.
DR   OMA; YHDPITH; -.
DR   OrthoDB; 1922654at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR038722; Ner_HTH_dom.
DR   Pfam; PF13693; HTH_35; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..92
FT                   /note="Sugar fermentation stimulation protein B"
FT                   /id="PRO_0000062782"
FT   DNA_BIND        50..69
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   92 AA;  10495 MW;  4B3859604F4259EC CRC64;
     MESNFIDWHP ADIIAGLRKK GTSMAAESRR NGLSSSTLAN ALSRPWPKGE MIIAKALGTD
     PWVIWPSRYH DPQTHEFIDR TQLMRSYTKP KK