ID   SFT2B_RAT               Reviewed;         157 AA.
AC   Q4FZV2;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Vesicle transport protein SFT2B;
DE   AltName: Full=SFT2 domain-containing protein 2;
GN   Name=Sft2d2 {ECO:0000250|UniProtKB:O95562};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved in fusion of retrograde transport vesicles
CC       derived from an endocytic compartment with the Golgi complex.
CC       {ECO:0000250|UniProtKB:P38166}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the SFT2 family. {ECO:0000255}.
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DR   EMBL; BC099092; AAH99092.1; -; mRNA.
DR   RefSeq; NP_001029183.1; NM_001034011.1.
DR   AlphaFoldDB; Q4FZV2; -.
DR   STRING; 10116.ENSRNOP00000068143; -.
DR   PaxDb; Q4FZV2; -.
DR   GeneID; 360868; -.
DR   KEGG; rno:360868; -.
DR   UCSC; RGD:1310623; rat.
DR   CTD; 375035; -.
DR   RGD; 1310623; Sft2d2.
DR   eggNOG; KOG2887; Eukaryota.
DR   InParanoid; Q4FZV2; -.
DR   OrthoDB; 1476123at2759; -.
DR   PhylomeDB; Q4FZV2; -.
DR   TreeFam; TF315157; -.
DR   PRO; PR:Q4FZV2; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR   InterPro; IPR011691; Vesicle_transpt_SFT2.
DR   PANTHER; PTHR23137; PTHR23137; 1.
DR   Pfam; PF04178; Got1; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Membrane; Phosphoprotein; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..157
FT                   /note="Vesicle transport protein SFT2B"
FT                   /id="PRO_0000238612"
FT   TOPO_DOM        1..36
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        58..61
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        83..96
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        118..120
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        142..157
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:O95562"
FT   MOD_RES         9
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95562"
SQ   SEQUENCE   157 AA;  17511 MW;  F70694C7D3180C39 CRC64;
     MDKLKKVLSG QDTEDRSGLS EVVESSSLSW STRIKGFIVC FALGILCSLL GTLLLWVSRK
     GLFAVFYTLG NITSIGSTMF LMGPLKQLKR MFEPTRLIAT ILVLLFFVLT LCSAFLWNKG
     LALIFCILQS LALTWYSLSY IPYARDAVKK CFAVCLT