ID   BGLH_SHIFL              Reviewed;         538 AA.
AC   Q83J01; Q7UB08;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 5.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Putative outer membrane porin BglH;
DE   Flags: Precursor;
GN   Name=bglH; OrderedLocusNames=SF3737, S4035;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: May be a sugar porin with a broad carbohydrate specificity.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN45182.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAP19015.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE005674; AAN45182.2; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014073; AAP19015.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_709475.2; NC_004337.2.
DR   RefSeq; WP_000489690.1; NZ_UIPU01000180.1.
DR   AlphaFoldDB; Q83J01; -.
DR   SMR; Q83J01; -.
DR   STRING; 198214.SF3737; -.
DR   EnsemblBacteria; AAN45182; AAN45182; SF3737.
DR   EnsemblBacteria; AAP19015; AAP19015; S4035.
DR   GeneID; 1026158; -.
DR   KEGG; sfl:SF3737; -.
DR   KEGG; sft:NCTC1_04032; -.
DR   KEGG; sfx:S4035; -.
DR   PATRIC; fig|198214.7.peg.4411; -.
DR   HOGENOM; CLU_032473_2_1_6; -.
DR   OrthoDB; 1013077at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034219; P:carbohydrate transmembrane transport; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   InterPro; IPR021570; LamB-type_porin_N_dom.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
DR   Pfam; PF11471; Sugarporin_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..538
FT                   /note="Putative outer membrane porin BglH"
FT                   /id="PRO_0000355025"
FT   REGION          52..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  60658 MW;  AEA2023538B57BB0 CRC64;
     MFRQNLITSA ILLMAPLAFS AQSLAESLTV EQRLELLEKA LRETQSELKK YKDEEKKKYT
     PATVNRSVST NDQGYAANPF PTSSAAKPDA VLVKNEEKNA SETGSIYSSM TLKDFSKFVK
     DEIGFSYNGY YRSGWGTASH GSPKSWAIGS LGRFGNEYSG WFDLQLKQRV YNENGKRVDA
     VVMIDGNVGQ QYSTGWFGDN AGGENFMQFS DMYVTTKGFL PFAPEADFWV GKHGAPKIEI
     QMLDWKTQRT DAAAGVGLEN WKVGPGKIDI ALVREDVDDY DRSLQNKQQI NTHTIDLRYK
     DIPLWDKATL MVSGRYVTAN ESASEKDNQD NNGYYDWKDT WMFGTSLTQK FDKGGFNEFS
     FLVANNSIAR NFGRYAGASP FTTFNGRYYG DHTGGTAVRL TSQGEAYIGD HFIVANAIVY
     SFGNNIYSYE TGAHSDFESI RAVVRPAYIW DQYNQTGVEL GYFTQQNKDA NSNKFNESGY
     KTTLFHTFKV NTSMLTSRLE IRFYATYIKA LENELDGFTF EDNKDAQFAV GAQAEIWW