ID   SG1C2_HUMAN             Reviewed;          95 AA.
AC   P0DMR2;
DT   26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT   26-NOV-2014, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Secretoglobin family 1C member 2;
DE   Flags: Precursor;
GN   Name=SCGB1C2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
CC   -!- INTERACTION:
CC       P0DMR2; Q12797-6: ASPH; NbExp=3; IntAct=EBI-12947705, EBI-12092171;
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P11684}.
CC   -!- SIMILARITY: Belongs to the secretoglobin family. {ECO:0000305}.
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DR   EMBL; AC240565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS73933.1; -.
DR   RefSeq; NP_001091079.1; NM_001097610.2.
DR   AlphaFoldDB; P0DMR2; -.
DR   SMR; P0DMR2; -.
DR   IntAct; P0DMR2; 2.
DR   STRING; 9606.ENSP00000471646; -.
DR   BioMuta; SCGB1C2; -.
DR   MassIVE; P0DMR2; -.
DR   PeptideAtlas; P0DMR2; -.
DR   PRIDE; P0DMR2; -.
DR   Ensembl; ENST00000595228.4; ENSP00000471646.2; ENSG00000268320.4.
DR   Ensembl; ENST00000613221.2; ENSP00000479313.1; ENSG00000277730.2.
DR   GeneID; 653486; -.
DR   KEGG; hsa:653486; -.
DR   MANE-Select; ENST00000595228.4; ENSP00000471646.2; NM_001097610.3; NP_001091079.1.
DR   UCSC; uc032eqd.2; human.
DR   CTD; 653486; -.
DR   DisGeNET; 653486; -.
DR   GeneCards; SCGB1C2; -.
DR   HGNC; HGNC:51242; SCGB1C2.
DR   HPA; ENSG00000268320; Tissue enhanced (pancreas, retina).
DR   neXtProt; NX_P0DMR2; -.
DR   VEuPathDB; HostDB:ENSG00000268320; -.
DR   eggNOG; ENOG502SDMQ; Eukaryota.
DR   GeneTree; ENSGT00940000155073; -.
DR   HOGENOM; CLU_184622_0_0_1; -.
DR   OMA; NAMAPDC; -.
DR   OrthoDB; 1523777at2759; -.
DR   PhylomeDB; P0DMR2; -.
DR   PathwayCommons; P0DMR2; -.
DR   BioGRID-ORCS; 653486; 10 hits in 155 CRISPR screens.
DR   ChiTaRS; SCGB1C2; human.
DR   GenomeRNAi; 653486; -.
DR   Pharos; P0DMR2; Tdark.
DR   PRO; PR:P0DMR2; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; P0DMR2; protein.
DR   Bgee; ENSG00000268320; Expressed in monocyte and 66 other tissues.
DR   Genevisible; P0DMR2; HS.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   CDD; cd00633; Secretoglobin; 1.
DR   InterPro; IPR016126; Secretoglobin.
DR   InterPro; IPR043215; Secretoglobin_1C-like.
DR   InterPro; IPR028659; Secretoglobin_1C1/2.
DR   InterPro; IPR035960; Secretoglobin_sf.
DR   PANTHER; PTHR10136; PTHR10136; 1.
DR   PANTHER; PTHR10136:SF8; PTHR10136:SF8; 1.
DR   Pfam; PF01099; Uteroglobin; 1.
DR   SUPFAM; SSF48201; SSF48201; 1.
DR   PROSITE; PS51311; SCGB; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..95
FT                   /note="Secretoglobin family 1C member 2"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000431381"
SQ   SEQUENCE   95 AA;  10457 MW;  F629AF06C96D2392 CRC64;
     MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL GKYNVNEDAK
     AAMTELKSCR DGLQPMHKAE LVKLLVQVLG SQDGA