ID   SGD1_SCHPO              Reviewed;         775 AA.
AC   O13971;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Suppressor of glycerol defect protein 1;
GN   Name=sgd1; ORFNames=SPAC24C9.11;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Involved in osmoregulatory glycerol response. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the CWC22 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB11268.1; -; Genomic_DNA.
DR   PIR; T38352; T38352.
DR   RefSeq; NP_594036.1; NM_001019461.2.
DR   AlphaFoldDB; O13971; -.
DR   SMR; O13971; -.
DR   BioGRID; 278107; 4.
DR   STRING; 4896.SPAC24C9.11.1; -.
DR   iPTMnet; O13971; -.
DR   MaxQB; O13971; -.
DR   PaxDb; O13971; -.
DR   PRIDE; O13971; -.
DR   EnsemblFungi; SPAC24C9.11.1; SPAC24C9.11.1:pep; SPAC24C9.11.
DR   GeneID; 2541610; -.
DR   KEGG; spo:SPAC24C9.11; -.
DR   PomBase; SPAC24C9.11; sgd1.
DR   VEuPathDB; FungiDB:SPAC24C9.11; -.
DR   eggNOG; KOG2141; Eukaryota.
DR   HOGENOM; CLU_006786_2_1_1; -.
DR   InParanoid; O13971; -.
DR   OMA; QFKQSIR; -.
DR   PhylomeDB; O13971; -.
DR   PRO; PR:O13971; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:PomBase.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   Pfam; PF02847; MA3; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   SMART; SM00544; MA3; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS51366; MI; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..775
FT                   /note="Suppressor of glycerol defect protein 1"
FT                   /id="PRO_0000316029"
FT   DOMAIN          262..463
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT   DOMAIN          565..689
FT                   /note="MI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT   REGION          1..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          152..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..31
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..46
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..93
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..219
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  87871 MW;  9013685BC390E4AA CRC64;
     MRPIKKSRSL KLPKSILEEI GESDSSARRG KRNHNLPHRE KRKFARISRG KNGYENRKIT
     EEGDSKSSEL NDDYLDAHRK SSTKKKSSQN KQAKESKLLD PIAFQHKIAL EEDDREIAHL
     EKMLGIKSKD KSAHSKIDKE FGWLLEDLDQ EIDDIGVPGT EDPSYGHSED SEVSDDTGDH
     GSVDELESER EGNSGEEEEE FHGFESNSDE FHQPETKPIR MDPLKPAVPS LPNANVGSKY
     VPPSLRKKLG GDKESEDALR LRRKLQGSLN KLSIANISSI IKEIEVLYME NSRHSVTSTI
     TNLLLQTVMG RESMLDQLAI VYAALATALY RIVGNDFGAH LLQTLVERFL QLYKSKEKEP
     LSSHKETSNL IVFFVELYNF QLVSCVLVYD LIRLFLRSLT ELNVEMLLKI VLNCGGQLRS
     DDPTSLQDIV TEMNLLLASA DPSTISVRTK FMVESITNLK ENKKTKVANA SAQSKFEAVN
     QLKKFLGSLG NRSLNAREPL RVTLEDIEQI ETKGRWWLVG ASWNNVPSGD NTLSTEALQD
     KKKSEELTAH SKILQAAKKL RLNSTLRTSI FVALVGSEDY IDAWERVLKL HLKRNQLPEI
     AYVILHCVGN EKLYNPFYGL VALKCCTLQH NLKKSFQFSL WDFFNELQPD DDSEEREISM
     RRIVNLAKLY ASLVIEAAQP LTILKHVDFM AINAQMQTFL LVFFTDIILG VKDDLQLVKI
     FENCKAEKNL SSKVDWFLKT YVRKNPLVDN SKKALFKSNL AMASAILQSI SKEEI