ID   SGF11_CULQU             Reviewed;         183 AA.
AC   B0W8L4;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=SAGA-associated factor 11 homolog {ECO:0000255|HAMAP-Rule:MF_03047};
GN   Name=Sgf11 {ECO:0000255|HAMAP-Rule:MF_03047}; ORFNames=CPIJ003322;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB;
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the transcription regulatory histone acetylation
CC       (HAT) complex SAGA, a multiprotein complex that activates transcription
CC       by remodeling chromatin and mediating histone acetylation and
CC       deubiquitination. Within the SAGA complex, participates in a subcomplex
CC       that specifically deubiquitinates histone H2B. The SAGA complex is
CC       recruited to specific gene promoters by activators, where it is
CC       required for transcription. {ECO:0000255|HAMAP-Rule:MF_03047}.
CC   -!- SUBUNIT: Component of some SAGA transcription coactivator-HAT
CC       complexes. Within the SAGA complex, participates in a subcomplex of
CC       SAGA called the DUB module (deubiquitination module) (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|HAMAP-Rule:MF_03047}.
CC   -!- DOMAIN: The long N-terminal helix forms part of the 'assembly lobe' of
CC       the SAGA deubiquitination module. {ECO:0000255|HAMAP-Rule:MF_03047}.
CC   -!- DOMAIN: The C-terminal SGF11-type zinc-finger domain forms part of the
CC       'catalytic lobe' of the SAGA deubiquitination module.
CC       {ECO:0000255|HAMAP-Rule:MF_03047}.
CC   -!- SIMILARITY: Belongs to the SGF11 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03047}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS231859; EDS39064.1; -; Genomic_DNA.
DR   RefSeq; XP_001845048.1; XM_001844996.1.
DR   AlphaFoldDB; B0W8L4; -.
DR   SMR; B0W8L4; -.
DR   STRING; 7176.CPIJ003322-PA; -.
DR   EnsemblMetazoa; XM_001844996.2; XP_001845048.2; LOC6034775.
DR   GeneID; 6034775; -.
DR   KEGG; cqu:CpipJ_CPIJ003322; -.
DR   VEuPathDB; VectorBase:CPIJ003322; -.
DR   VEuPathDB; VectorBase:CQUJHB017088; -.
DR   eggNOG; KOG2612; Eukaryota.
DR   HOGENOM; CLU_100743_0_0_1; -.
DR   InParanoid; B0W8L4; -.
DR   OMA; EDSTYRM; -.
DR   OrthoDB; 1386545at2759; -.
DR   PhylomeDB; B0W8L4; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0071819; C:DUBm complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0000124; C:SAGA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0016578; P:histone deubiquitination; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03047; Sgf11; 1.
DR   InterPro; IPR013246; SAGA_su_Sgf11.
DR   Pfam; PF08209; Sgf11; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..183
FT                   /note="SAGA-associated factor 11 homolog"
FT                   /id="PRO_0000367520"
FT   ZN_FING         98..119
FT                   /note="SGF11-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03047"
FT   REGION          140..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   183 AA;  20451 MW;  895B9AB6B288BECD CRC64;
     MSESEPVHIE YADETELLTE FRNFMSDPDT REKAANYLLN SLIDESILGI VFEVHHAYKT
     GSVAAIEGQP EDPKSFTIVD MPDMDVFGST NSKKAIDCSC PNCNRIVAAS RFAPHLEKCM
     GMGRNSSRIA SRRIANTRDG GNYFGADEDD EDDADWSGEK RKKKIAPVRT NGSKKNVMKI
     YFL