ID   SGF1_BOMMO              Reviewed;         349 AA.
AC   Q17241;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Silk gland factor 1;
DE            Short=SGF-1;
GN   Name=SGF1;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Silk gland;
RX   PubMed=7721856; DOI=10.1074/jbc.270.16.9340;
RA   Mach V., Takiya S., Ohno K., Handa H., Imai T., Suzuki Y.;
RT   "Silk gland factor-1 involved in the regulation of Bombyx sericin-1 gene
RT   contains fork head motif.";
RL   J. Biol. Chem. 270:9340-9346(1995).
CC   -!- FUNCTION: Regulates the transcription of the sericin-1 gene via
CC       interaction with the SA site.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; D38514; BAA07523.1; -; mRNA.
DR   PIR; A56365; A56365.
DR   RefSeq; NP_001037329.1; NM_001043864.1.
DR   AlphaFoldDB; Q17241; -.
DR   SMR; Q17241; -.
DR   STRING; 7091.BGIBMGA005101-TA; -.
DR   iPTMnet; Q17241; -.
DR   GeneID; 692754; -.
DR   KEGG; bmor:692754; -.
DR   CTD; 692754; -.
DR   eggNOG; KOG3563; Eukaryota.
DR   HOGENOM; CLU_027910_1_0_1; -.
DR   InParanoid; Q17241; -.
DR   OrthoDB; 1181467at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00059; FH; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR013638; Fork-head_N.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR018122; TF_fork_head_CS_1.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00250; Forkhead; 1.
DR   Pfam; PF08430; Forkhead_N; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00657; FORK_HEAD_1; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..349
FT                   /note="Silk gland factor 1"
FT                   /id="PRO_0000091916"
FT   DNA_BIND        112..203
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00089"
FT   REGION          82..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  38798 MW;  05E1119D29089A74 CRC64;
     MISQKLSYGD VPTSASLSSL SPGLAPPYVN GMGCMPAQPY PNLYSNNMVA GGSCMGSPSV
     GYSPPSTMAS CMGGAGAVPY GSLPREQEAA SPTSALQRAR NDKTYRRSYT HAKPPYSYIS
     LITMAIQNNP SRMLTLSEIY QFIMDLFPFY RQNQQRWQNS IRHSLSFNDC FVKVPRTPDK
     PGKGSFWTLH PDSGNMFENG CFLRRQKRFK DEKKETLRQA QKAQQTHGHH GGSHDKRGEH
     GHDKSAPPGP GEDKEMRDEL LAQLHAAPEL CLPEHTPLAL EHYAQLKQEP SGYAPAQHPF
     SITRLLPGAD TKADLKMYDV NYGYGHSPAD NYYQSPLYHH HHAHAQPPL