ID   SGF29_CHICK             Reviewed;         293 AA.
AC   Q5ZL38;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=SAGA-associated factor 29 {ECO:0000305};
DE   AltName: Full=Coiled-coil domain-containing protein 101;
DE   AltName: Full=SAGA complex-associated factor 29 {ECO:0000250|UniProtKB:Q96ES7};
GN   Name=SGF29 {ECO:0000250|UniProtKB:Q96ES7}; Synonyms=CCDC101;
GN   ORFNames=RCJMB04_7p7;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Chromatin reader component of some histone acetyltransferase
CC       (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes.
CC       SGF29 specifically recognizes and binds methylated 'Lys-4' of histone
CC       H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the
CC       SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me.
CC       {ECO:0000250|UniProtKB:Q96ES7}.
CC   -!- SUBUNIT: Interacts with dimethylated and trimethylated 'Lys-4' of
CC       histone H3 (H3K4me2 and H3K4me3), with a preference for the
CC       trimethylated form (H3K4me3). Component of some SAGA-type complexes.
CC       Component of the ADA2A-containing complex (ATAC).
CC       {ECO:0000250|UniProtKB:P0C606, ECO:0000250|UniProtKB:Q96ES7}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P0C606}.
CC   -!- DOMAIN: The SGF29 C-terminal (also named tudor-like) domain mediates
CC       binding to methylated 'Lys-4' of histone H3 (H3K4me).
CC       {ECO:0000255|PROSITE-ProRule:PRU00851}.
CC   -!- SIMILARITY: Belongs to the SGF29 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00851}.
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DR   EMBL; AJ719896; CAG31555.1; -; mRNA.
DR   RefSeq; NP_001026469.1; NM_001031298.1.
DR   AlphaFoldDB; Q5ZL38; -.
DR   SMR; Q5ZL38; -.
DR   STRING; 9031.ENSGALP00000037055; -.
DR   PaxDb; Q5ZL38; -.
DR   Ensembl; ENSGALT00000037849; ENSGALP00000037055; ENSGALG00000020590.
DR   Ensembl; ENSGALT00000079423; ENSGALP00000049776; ENSGALG00000020590.
DR   GeneID; 424726; -.
DR   KEGG; gga:424726; -.
DR   CTD; 112869; -.
DR   VEuPathDB; HostDB:geneid_424726; -.
DR   eggNOG; KOG3038; Eukaryota.
DR   GeneTree; ENSGT00390000015229; -.
DR   HOGENOM; CLU_056816_0_0_1; -.
DR   InParanoid; Q5ZL38; -.
DR   OMA; TYIAKMG; -.
DR   PhylomeDB; Q5ZL38; -.
DR   PRO; PR:Q5ZL38; -.
DR   Proteomes; UP000000539; Chromosome 8.
DR   Bgee; ENSGALG00000020590; Expressed in lung and 12 other tissues.
DR   ExpressionAtlas; Q5ZL38; baseline and differential.
DR   GO; GO:0140672; C:ATAC complex; ISS:UniProtKB.
DR   GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR   GO; GO:0070461; C:SAGA-type complex; ISS:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; ISS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0016573; P:histone acetylation; ISS:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IBA:GO_Central.
DR   InterPro; IPR037802; SGF29.
DR   InterPro; IPR010750; SGF29_tudor-like_dom.
DR   PANTHER; PTHR21539; PTHR21539; 1.
DR   Pfam; PF07039; DUF1325; 1.
DR   PROSITE; PS51518; SGF29_C; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator; Coiled coil; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..293
FT                   /note="SAGA-associated factor 29"
FT                   /id="PRO_0000274270"
FT   DOMAIN          152..293
FT                   /note="SGF29 C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
FT   REGION          194..196
FT                   /note="Histone H3K4me3 N-terminus binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
FT   REGION          240..243
FT                   /note="Histone H3K4me3 N-terminus binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
FT   REGION          264..266
FT                   /note="Histone H3K4me3 binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
FT   COILED          12..88
FT                   /evidence="ECO:0000255"
FT   SITE            238
FT                   /note="Histone H3K4me3 binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
FT   SITE            245
FT                   /note="Histone H3K4me3 binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00851"
SQ   SEQUENCE   293 AA;  33112 MW;  3141BBE26D034996 CRC64;
     MALVSADSRI AELLAELQRL LGHTQEERSR SEHNLINIQK THERMQTENK ISPYYRTKLR
     GLYTTAKADA EAECNILRKA LDKIAEIKSL LEERRIAAKI AGIYSDAEPP RKTMRRGVLM
     TLLQQSAMTL PLWIGKPGDK PPPLCGAMPA AGDYVAKPGD KVAARVKAVD GDEQWILAEV
     VSYSHAANKY EVDDIDEEGK ERHTLSRRRV IPLPQWKANP ETDPEALFQR EQLVLALYPQ
     TTCFYRALIH APPQRPQDDY SVLFEDTSYA DGYSPPLNVA QRYVVACKET KKK