ID   SGO1_CAEBR              Reviewed;         306 AA.
AC   Q60ZS1; A8XRJ3;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Shugoshin;
GN   Name=sgo-1; ORFNames=CBG17678;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Plays a central role in chromosome cohesion during cell
CC       division by preventing premature dissociation of cohesin complex from
CC       centromeres after prophase, when most of cohesin complex dissociates
CC       from chromosomes arms. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the shugoshin family. {ECO:0000305}.
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DR   EMBL; HE600976; CAP35267.1; -; Genomic_DNA.
DR   RefSeq; XP_002634335.1; XM_002634289.1.
DR   AlphaFoldDB; Q60ZS1; -.
DR   SMR; Q60ZS1; -.
DR   STRING; 6238.CBG17678; -.
DR   GeneID; 8576330; -.
DR   KEGG; cbr:CBG_17678; -.
DR   CTD; 8576330; -.
DR   WormBase; CBG17678; CBP41617; WBGene00037243; Cbr-sgo-1.
DR   eggNOG; ENOG502RT7Z; Eukaryota.
DR   HOGENOM; CLU_858533_0_0_1; -.
DR   InParanoid; Q60ZS1; -.
DR   OMA; DEPMPFI; -.
DR   OrthoDB; 1385559at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045132; P:meiotic chromosome segregation; IEA:InterPro.
DR   InterPro; IPR011515; Shugoshin_C.
DR   InterPro; IPR011516; Shugoshin_N.
DR   Pfam; PF07557; Shugoshin_C; 1.
DR   Pfam; PF07558; Shugoshin_N; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition;
KW   Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..306
FT                   /note="Shugoshin"
FT                   /id="PRO_0000055441"
FT   REGION          122..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          223..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          28..75
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        134..161
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..185
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..251
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..283
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..298
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  34150 MW;  92D435C07B44B6C4 CRC64;
     MNAKAAQSLF GAIASSKKAP TREEPAVNFK STNESLIKKN LQLKQQLSQC TKALEKLRNE
     NIALREQNQE LIDATLDEKM ERIVEQRVKS RLAHAAVLHK KLVQNIQQTG LELGGIFKDM
     EPEPSGMVTR RAPKMECNLE KLDESPVRNF PRSDYEEENK SPMDIQNGPS SSSSMTQNLE
     NGTPRMAQRA SKGRRSELFH SLHENVPEEA APAVGYKRAP LLIAPSETPG GPPKKAPPRK
     APTPRFKKPS TPAPAPISDD AEMPSTVRRQ RSAKMNIKSM KEPSVNSKLR RPGKHDEPMP
     FIDTFF