ID   SGO1_EMENI              Reviewed;         479 AA.
AC   Q5BDI1; C8VRM2;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Shugoshin;
GN   Name=sgo1; ORFNames=AN1399;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Plays a central role in chromosome cohesion during cell
CC       division by preventing premature dissociation of cohesin complex from
CC       centromeres after prophase, when most of cohesin complex dissociates
CC       from chromosomes arms. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the shugoshin family. {ECO:0000305}.
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DR   EMBL; AACD01000020; EAA65155.1; -; Genomic_DNA.
DR   EMBL; BN001308; CBF87574.1; -; Genomic_DNA.
DR   RefSeq; XP_659003.1; XM_653911.1.
DR   AlphaFoldDB; Q5BDI1; -.
DR   SMR; Q5BDI1; -.
DR   STRING; 227321.Q5BDI1; -.
DR   EnsemblFungi; CBF87574; CBF87574; ANIA_01399.
DR   EnsemblFungi; EAA65155; EAA65155; AN1399.2.
DR   GeneID; 2877169; -.
DR   KEGG; ani:AN1399.2; -.
DR   eggNOG; ENOG502SFX7; Eukaryota.
DR   HOGENOM; CLU_013723_2_0_1; -.
DR   InParanoid; Q5BDI1; -.
DR   OMA; NNDHLAG; -.
DR   OrthoDB; 1291337at2759; -.
DR   Proteomes; UP000000560; Chromosome VIII.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0000793; C:condensed chromosome; IEA:UniProt.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006336; P:DNA replication-independent chromatin assembly; IBA:GO_Central.
DR   InterPro; IPR038889; Shugoshin.
DR   InterPro; IPR011516; Shugoshin_N.
DR   PANTHER; PTHR21577; PTHR21577; 1.
DR   Pfam; PF07558; Shugoshin_N; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition;
KW   Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..479
FT                   /note="Shugoshin"
FT                   /id="PRO_0000055447"
FT   REGION          109..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          220..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..479
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          36..76
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        221..239
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..306
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        316..331
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..352
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        376..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..472
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  53260 MW;  82A9119B4F2CFD4D CRC64;
     MARLNESTAS SEPIEILKRR FVRQNREIAR VNSIQSLRIR SLESEVSNLL SENVSLREQI
     ITLTQELERF EAARTLHDGV YDVKARLDSK LVELGNLITE LGSLPRRYSR AVRENGEPAP
     ARQSRESGPK EVDDTDPEPN LGFLDGRLPV IMEDKLYPRR TLTAQEVQEL RDSDTDGPNC
     SGFEDSSISP KQRVEYDEAA TGGPAYFIDT NTIVEEIENE HSLPPNLETR RKKKIGPATV
     NKDQADTRPI SLLDSKFTRK CGAKRKFSAE DDESLFESSP SEDDEFQFSR PAQSPKLFSQ
     NEHASADDGS GELRRPIQSP TLSSQNDHSP VKMKPQSERS IAHVHGERRV LEPKSTNTNI
     LSPAKPSIMK DYNQNHDFGY NEKSEKPLPR QGKGAVDGSK NASPKKSSTR TPVFGNDGNK
     SGNKQKKSGA IKSNTPSLDG IEDSEIATTA DMPSTRPSRR RGTVSQPESH KTEGISMPP