ID   SGO1_MAIZE              Reviewed;         474 AA.
AC   Q4QSC8; A0A1D6HVU1;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2018, sequence version 2.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Shugoshin-1 {ECO:0000303|PubMed:15916952};
DE   AltName: Full=ZmSGO1 {ECO:0000303|PubMed:15916952};
GN   Name=SGO1 {ECO:0000303|PubMed:15916952};
GN   ORFNames=ZEAMMB73_Zm00001d019148 {ECO:0000312|EMBL:ONM52352.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, AND TISSUE
RP   SPECIFICITY.
RX   PubMed=15916952; DOI=10.1016/j.cub.2005.04.049;
RA   Hamant O., Golubovskaya I., Meeley R., Fiume E., Timofejeva L.,
RA   Schleiffer A., Nasmyth K., Cande W.Z.;
RT   "A REC8-dependent plant Shugoshin is required for maintenance of
RT   centromeric cohesion during meiosis and has no mitotic functions.";
RL   Curr. Biol. 15:948-954(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. B73;
RX   PubMed=19965430; DOI=10.1126/science.1178534;
RA   Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA   Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA   Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA   Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA   Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA   Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA   Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA   Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA   Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA   Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA   Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA   Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA   Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA   Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA   Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA   Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA   Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA   Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA   Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA   Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA   SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA   Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA   Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA   Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA   Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA   Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT   "The B73 maize genome: complexity, diversity, and dynamics.";
RL   Science 326:1112-1115(2009).
CC   -!- FUNCTION: Plays a central role in chromosome cohesion during meiosis I
CC       by preventing premature dissociation of cohesin complex from
CC       centromeres after prophase, when most of cohesin complex dissociates
CC       from chromosomes arms. Required for maintenance of centromeric cohesion
CC       before prophase II and correct segregation of chromatids during meiosis
CC       II. Has apparently no function in mitosis.
CC       {ECO:0000269|PubMed:15916952}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15916952}.
CC       Chromosome, centromere {ECO:0000269|PubMed:15916952}. Note=Localizes to
CC       the centromere during meiosis I. REC8 is required for centromeric
CC       localization.
CC   -!- TISSUE SPECIFICITY: Highly expressed in tissues containing meiocytes.
CC       Expressed at much lower level in leaves and pollen-containing flowers.
CC       {ECO:0000269|PubMed:15916952}.
CC   -!- SIMILARITY: Belongs to the shugoshin family. {ECO:0000305}.
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DR   EMBL; AY964185; AAY32925.1; -; mRNA.
DR   EMBL; CM007650; ONM52352.1; -; Genomic_DNA.
DR   RefSeq; NP_001105791.1; NM_001112321.1.
DR   AlphaFoldDB; Q4QSC8; -.
DR   SMR; Q4QSC8; -.
DR   STRING; 4577.GRMZM2G074082_P01; -.
DR   PRIDE; Q4QSC8; -.
DR   EnsemblPlants; Zm00001eb303090_T004; Zm00001eb303090_P004; Zm00001eb303090.
DR   GeneID; 606461; -.
DR   Gramene; Zm00001eb303090_T004; Zm00001eb303090_P004; Zm00001eb303090.
DR   KEGG; zma:606461; -.
DR   eggNOG; ENOG502RYDC; Eukaryota.
DR   OMA; MRIDANK; -.
DR   OrthoDB; 947253at2759; -.
DR   Proteomes; UP000007305; Chromosome 7.
DR   ExpressionAtlas; Q4QSC8; baseline and differential.
DR   GO; GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0034090; P:maintenance of meiotic sister chromatid cohesion; IEA:InterPro.
DR   GO; GO:0045144; P:meiotic sister chromatid segregation; IMP:UniProtKB.
DR   InterPro; IPR044693; SGO_plant.
DR   InterPro; IPR011515; Shugoshin_C.
DR   PANTHER; PTHR34373; PTHR34373; 1.
DR   Pfam; PF07557; Shugoshin_C; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition;
KW   Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..474
FT                   /note="Shugoshin-1"
FT                   /id="PRO_0000055444"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          422..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..205
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..345
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        380
FT                   /note="E -> K (in Ref. 1; AAY32925)"
SQ   SEQUENCE   474 AA;  52159 MW;  4C11743AC5C2E324 CRC64;
     MTSTAAEGAG SGSLNPPHSN PSGDGGPRIR SPPGKGNKPV ALADITNTGK PNAARSITVP
     DLVKENTKLL TLLNEKTKII DLSRVEIYKL RLALQASKQQ NLHLTQTNSQ MLAEINTGKD
     RIKMLQHELS CTTALLKVKD SELDRKKNAG NVQQKGVKSQ VLKTKASTVA VEAHHVGDSV
     TSGVEHHVVE SQSAVSSNTV CQEPPQDGKQ KRMPQRRRSS RLNQGSCEIR GVSQNTLHEN
     PVVPVAPSTL SLEKQYGQTT GKHMKSLQNE CSATVHEVIM ASEFEKTEIN ELPQKTDLKE
     IPEACSSETE VQSHKIGDKA FNSKQNHLTG SQSSLSFNTV DTPEPPEDNT VKRCSKKRSS
     IEDVNAKLDT ITSEPLRHEE KRKSRRKISA RLNSVSSEHT DIVVETEHKD VIVSLAGSTS
     NVSMEQRTNQ EQDGDCFSRK SNENQILGRR SLRRAAEKVV SYKEMPLNVK MRRP