SGO1_ORYSJ
ID SGO1_ORYSJ Reviewed; 486 AA.
AC E3VXF2; A0A0P0VR49; C7IZ57; Q69QY9;
DT 20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 1.
DT 03-AUG-2022, entry version 41.
DE RecName: Full=Shugoshin-1 {ECO:0000303|PubMed:21615569};
DE Short=OsSGO1 {ECO:0000303|PubMed:21615569};
GN Name=SGO1 {ECO:0000303|PubMed:21615569};
GN OrderedLocusNames=Os02g0799100 {ECO:0000312|EMBL:BAS81391.1},
GN LOC_Os02g55570 {ECO:0000305};
GN ORFNames=OJ1695_D07.19 {ECO:0000312|EMBL:BAD36062.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=21615569; DOI=10.1111/j.1365-313x.2011.04615.x;
RA Wang M., Tang D., Wang K., Shen Y., Qin B., Miao C., Li M., Cheng Z.;
RT "OsSGO1 maintains synaptonemal complex stabilization in addition to
RT protecting centromeric cohesion during rice meiosis.";
RL Plant J. 67:583-594(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Plays a central role in chromosome cohesion during meiosis I
CC by preventing premature dissociation of cohesin complex from
CC centromeres after prophase, when most of cohesin complex dissociates
CC from chromosomes arms. Required for the timely assembly and maintenance
CC of synaptonemal complex (SC) during early prophase I. Required for
CC maintenance of centromeric cohesion before prophase II and correct
CC segregation of chromatids during meiosis II. Has apparently no function
CC in mitosis. {ECO:0000269|PubMed:21615569}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:21615569}.
CC Chromosome, centromere {ECO:0000269|PubMed:21615569}. Note=Transfers
CC from nucleoli onto centromeric regions at the onset of prophase in both
CC mitosis and meiosis. AM1 is required for centromeric localization.
CC {ECO:0000269|PubMed:21615569}.
CC -!- TISSUE SPECIFICITY: Highly expressed in roots. Expressed in panicles.
CC Expressed at low levels in leaves. {ECO:0000269|PubMed:21615569}.
CC -!- DISRUPTION PHENOTYPE: Complete sterility, due to shrunken and inviable
CC pollen grains. Premature separation of sister chromatids before
CC metaphase II causes defective meiosis of the male meiocyte.
CC {ECO:0000269|PubMed:21615569}.
CC -!- SIMILARITY: Belongs to the shugoshin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD36062.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAH91911.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAS81391.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; HQ333477; ADO32586.1; -; mRNA.
DR EMBL; AP005295; BAD36062.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAH91911.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; BAS81391.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015626584.1; XM_015771098.1.
DR RefSeq; XP_015626586.1; XM_015771100.1.
DR AlphaFoldDB; E3VXF2; -.
DR SMR; E3VXF2; -.
DR STRING; 4530.OS02T0799100-01; -.
DR PRIDE; E3VXF2; -.
DR EnsemblPlants; Os02t0799100-02; Os02t0799100-02; Os02g0799100.
DR GeneID; 9266998; -.
DR Gramene; Os02t0799100-02; Os02t0799100-02; Os02g0799100.
DR eggNOG; ENOG502RYDC; Eukaryota.
DR HOGENOM; CLU_028640_1_0_1; -.
DR OrthoDB; 947253at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IDA:UniProtKB.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0034090; P:maintenance of meiotic sister chromatid cohesion; IEA:InterPro.
DR GO; GO:0045144; P:meiotic sister chromatid segregation; IMP:UniProtKB.
DR InterPro; IPR044693; SGO_plant.
DR InterPro; IPR011515; Shugoshin_C.
DR PANTHER; PTHR34373; PTHR34373; 1.
DR Pfam; PF07557; Shugoshin_C; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition;
KW Coiled coil; Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..486
FT /note="Shugoshin-1"
FT /id="PRO_0000444506"
FT REGION 137..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 71..154
FT /evidence="ECO:0000255"
FT COMPBIAS 194..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 53381 MW; 987286590EFC6BB0 CRC64;
MAAAAGAAAR GGGVIPAGKG GSLRSPGKPV VLADITNTGR PNPTGSVHAI ADVLKENAKL
RHLLAERNKV IEVSRVELQK IRLALQAMQQ KNLQLVQANS QMFAEINQGK DRIKLLQHEL
ACTIAVLKVK GSELEKMSKT SNNQQNRAKI LEKKTRSSKC APTKAHQMAA GSIREHLVEI
QSAVPSYTSC HEPPQDKTNK RCTNRRKSES CEVTMDTNTV QHSCRPHVEY NGSSHDDDPR
KTRRRRSARL NPGSFEVAEI CDKLHEDATV PSAPSSNVPK LQEPNAGKDM ICGGKMKSLQ
KELPCDAIAQ VVEAPELKEI QEAGSSVAGG EAHKFDIEDP EPPRKSMRID ANKRKLESFE
SRLASNKEDC INAICDSTSS VPIQHEQKRK LSRRKSSRLD PGPWEVTNGT FEIVQEDTVA
PSAPSSSNAL IEQTKNDMQN DRSCSTKPSD EQVIGRRSSV GRPSRRAAEK IVSYKEVPLN
IKMRRP
