ID   SGRR_PECAS              Reviewed;         552 AA.
AC   Q6D0F8;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=HTH-type transcriptional regulator SgrR {ECO:0000255|HAMAP-Rule:MF_01449};
GN   Name=sgrR {ECO:0000255|HAMAP-Rule:MF_01449}; OrderedLocusNames=ECA3841;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Activates the small RNA gene sgrS under glucose-phosphate
CC       stress conditions as well as yfdZ. Represses its own transcription
CC       under both stress and non-stress conditions. Might act as a sensor of
CC       the intracellular accumulation of phosphoglucose by binding these
CC       molecules in its C-terminal solute-binding domain. {ECO:0000255|HAMAP-
CC       Rule:MF_01449}.
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DR   EMBL; BX950851; CAG76739.1; -; Genomic_DNA.
DR   RefSeq; WP_011095339.1; NC_004547.2.
DR   AlphaFoldDB; Q6D0F8; -.
DR   SMR; Q6D0F8; -.
DR   STRING; 218491.ECA3841; -.
DR   EnsemblBacteria; CAG76739; CAG76739; ECA3841.
DR   KEGG; eca:ECA3841; -.
DR   PATRIC; fig|218491.5.peg.3896; -.
DR   eggNOG; COG4533; Bacteria.
DR   HOGENOM; CLU_017028_12_3_6; -.
DR   OMA; WLTWQAE; -.
DR   OrthoDB; 162819at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01449; HTH_type_SgrR; 1.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR000914; SBP_5_dom.
DR   InterPro; IPR025370; SgrR_HTH_N.
DR   InterPro; IPR023767; Tscrpt_reg_SgrR.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   Pfam; PF12793; SgrR_N; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..552
FT                   /note="HTH-type transcriptional regulator SgrR"
FT                   /id="PRO_0000309240"
FT   REGION          163..493
FT                   /note="Solute-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01449"
SQ   SEQUENCE   552 AA;  64712 MW;  EB194AB4AE92F948 CRC64;
     MSSPRLQQQF IRLWQHFQGQ TTDTTLQELT GVLNCSRRHI RSLLNAMQLE GWLIWQAEAG
     RGKRSQLSFV YTGLALQQQR AEDLLEQDRI EQLVQLVGDK EAVRQMLLSH LGRSFRQGKH
     ILRILYYRPL RNLLPSSALR RSEMHIARQI FSGLTNINEE NGELKPDLAH HWQMLAPLHW
     RFYLRPAIRF HHGRELTMDD ITTSLSRLIP LPLFSHIEAV NSPMPFVIDI RLSSPDKWLP
     WLLASVHAMI LPQEWQTLPN FAQHPIGTGP YAVVRNNSSQ LKIRAFDDYF GYRALIDEVN
     IWVLPDEPEE MPVSVQFQSD DSHHEQLESR MEEGGYFLLF DKRSPLNQRP EALRWLRQVF
     NPVSLLSHAN TSNQRDWSPA YSLLPRWHHH HPDTPQSIPD GLTDVTLTFY QEHPEYRILS
     EIMRTLLAQQ GVTLHLQTIS YEDWYQGNAE SDIWFGSLNC YLPLEFSLFA MLYELPLVQH
     CLNDDLDTDA QQWRSHTLPM AEWCEKLIKS GQLHPLLHHW LQLQGQRSMR GVRMNMLGWF
     DFKSAWFAPP ER