ID   SGS3_ORYSJ              Reviewed;         609 AA.
AC   Q2QWE9; A0A0P0Y7V7; A3CFR9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Protein SUPPRESSOR OF GENE SILENCING 3 homolog;
DE            Short=OsSGS3;
GN   Name=SGS3; OrderedLocusNames=Os12g0197500, LOC_Os12g09580;
GN   ORFNames=OsJ_034141;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Required for post-transcriptional gene silencing and natural
CC       virus resistance. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SGS3 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAZ19932.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DP000011; ABA96655.1; -; Genomic_DNA.
DR   EMBL; AP008218; BAF29379.1; -; Genomic_DNA.
DR   EMBL; AP014968; BAT16246.1; -; Genomic_DNA.
DR   EMBL; CM000149; EAZ19932.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015620650.1; XM_015765164.1.
DR   AlphaFoldDB; Q2QWE9; -.
DR   SMR; Q2QWE9; -.
DR   STRING; 4530.OS12T0197500-01; -.
DR   PaxDb; Q2QWE9; -.
DR   PRIDE; Q2QWE9; -.
DR   EnsemblPlants; Os12t0197500-01; Os12t0197500-01; Os12g0197500.
DR   GeneID; 4351724; -.
DR   Gramene; Os12t0197500-01; Os12t0197500-01; Os12g0197500.
DR   KEGG; osa:4351724; -.
DR   eggNOG; ENOG502QPU5; Eukaryota.
DR   InParanoid; Q2QWE9; -.
DR   OMA; DFERMQQ; -.
DR   OrthoDB; 370807at2759; -.
DR   Proteomes; UP000000763; Chromosome 12.
DR   Proteomes; UP000007752; Chromosome 12.
DR   Proteomes; UP000059680; Chromosome 12.
DR   ExpressionAtlas; Q2QWE9; baseline and differential.
DR   Genevisible; Q2QWE9; OS.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051607; P:defense response to virus; IEA:InterPro.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
DR   CDD; cd12266; RRM_like_XS; 1.
DR   Gene3D; 3.30.70.2890; -; 1.
DR   InterPro; IPR044287; SGS3.
DR   InterPro; IPR005380; XS_domain.
DR   InterPro; IPR038588; XS_domain_sf.
DR   InterPro; IPR005381; Znf-XS_domain.
DR   PANTHER; PTHR46602; PTHR46602; 1.
DR   Pfam; PF03468; XS; 1.
DR   Pfam; PF03470; zf-XS; 1.
PE   3: Inferred from homology;
KW   Antiviral protein; Coiled coil; Cytoplasm; Reference proteome;
KW   RNA-mediated gene silencing.
FT   CHAIN           1..609
FT                   /note="Protein SUPPRESSOR OF GENE SILENCING 3 homolog"
FT                   /id="PRO_0000333291"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          116..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          420..473
FT                   /evidence="ECO:0000255"
FT   COILED          545..584
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        40..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..166
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   609 AA;  69444 MW;  07409C3BF685331D CRC64;
     MASAGDRRGG GGPPGSGDDS GGGWETVEKR VKKPAQQVGK GQWGQWNSPN AAPAPTAPRS
     GSGAFHHSGN TLVRHSDRRP ARGTPRPPPQ NRSIEAELQA PHGVVTAPLA NGWQWGARSC
     PPGTESKEGG LPLSGCDPET DNAEGYDTSD DDNDDDMSDD LSDDYDSDAS EKSFETRKNH
     KLFKGFFEVL EALSVEQLNE PTRQWHCPAC KNGPGAIDWY KGLQPLMTHA KTKGSIKVKR
     HRELASLLEE ELSRRGTSVV PSGEQFRKWK GLRESTDREI VWPPMVVVMN TVLEQDEDDK
     WKGMGNQELI DYFSEYAASK ARHAYGPNGH RGMSVLIFDS SAVGYMEAER LHDHFVRQRT
     DRNTWNSAHK VTFLPGGKRQ LYGFLATKDD METFNRHCHG KSRLKYEMRS YNEMVVTQMK
     QMSEDNQQLN YLKNKMVKKE QHSKLVEDTL SVVTQKLRET MEENTIVRNK AKEKHLEYEK
     EMKYQEEFFH DQIEKIHKAT EEKEIKFEKL LQEERAKARQ SDVDSGSTED RRQRKEKIQN
     FIDCQVKDVE EFEAERDKLI KLHEEKKVKL KKEYLAKEFE LEKELDTALT SLMDKHKPDI
     FKSSTSPST