ID   SGS_BPT7                Reviewed;          99 AA.
AC   P0DJY3;
DT   19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT   19-FEB-2014, sequence version 1.
DT   12-AUG-2020, entry version 17.
DE   RecName: Full=Protein suppressor of silencing;
DE   AltName: Full=Gene product 5.5;
GN   OrderedLocusNames=5.5;
OS   Escherichia phage T7 (Bacteriophage T7).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus.
OX   NCBI_TaxID=10760;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6864790; DOI=10.1016/s0022-2836(83)80282-4;
RA   Dunn J.J., Studier F.W.;
RT   "Complete nucleotide sequence of bacteriophage T7 DNA and the locations of
RT   T7 genetic elements.";
RL   J. Mol. Biol. 166:477-535(1983).
RN   [2]
RP   SEQUENCE REVISION.
RA   Dunn J.J., Studier F.W.;
RL   Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   FUNCTION, AND INTERACTION WITH HOST HNS.
RX   PubMed=21764926; DOI=10.1128/jb.05198-11;
RA   Ali S.S., Beckett E., Bae S.J., Navarre W.W.;
RT   "The 5.5 protein of phage T7 inhibits H-NS through interactions with the
RT   central oligomerization domain.";
RL   J. Bacteriol. 193:4881-4892(2011).
CC   -!- FUNCTION: Plays a role in the inhibition of gene silencing by the host
CC       nucleoid-associated protein H-NS/hns. Disrupts higher-order H-NS-DNA
CC       complexes. {ECO:0000269|PubMed:21764926}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=2; Synonyms=Protein suppressor of silencing;
CC         IsoId=P0DJY3-1; Sequence=Displayed;
CC       Name=1; Synonyms=Fusion protein 5.5/5.7;
CC         IsoId=P03787-1; Sequence=External;
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DR   EMBL; V01146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_041985.1; NC_001604.1. [P0DJY3-1]
DR   GeneID; 1261038; -.
DR   KEGG; vg:1261038; -.
DR   Proteomes; UP000000840; Genome.
DR   InterPro; IPR022611; Phage_T7_5.5.
DR   Pfam; PF11247; DUF2675; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Ribosomal frameshifting.
FT   CHAIN           1..99
FT                   /note="Protein suppressor of silencing"
FT                   /id="PRO_0000425444"
SQ   SEQUENCE   99 AA;  11206 MW;  14048A50BBABDA2C CRC64;
     MAMTKKFKVS FDVTAKMSSD VQAILEKDML HLCKQVGSGA IVPNGKQKEM IVQFLTHGME
     GLMTFVVRTS FREAIKDMHE EYADKDSFKQ SPATVREVF