SGTB_HUMAN
ID SGTB_HUMAN Reviewed; 304 AA.
AC Q96EQ0;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 159.
DE RecName: Full=Small glutamine-rich tetratricopeptide repeat-containing protein beta;
DE AltName: Full=Beta-SGT;
DE AltName: Full=Small glutamine-rich protein with tetratricopeptide repeats 2;
GN Name=SGTB; Synonyms=SGT2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Tobaben S., Stahl B.;
RL Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Uterus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-295 AND SER-297, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-297, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT "System-wide temporal characterization of the proteome and phosphoproteome
RT of human embryonic stem cell differentiation.";
RL Sci. Signal. 4:RS3-RS3(2011).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-297, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma, and Erythroleukemia;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
CC -!- FUNCTION: Co-chaperone that binds directly to HSC70 and HSP70 and
CC regulates their ATPase activity. {ECO:0000250}.
CC -!- SUBUNIT: Homooligomerize. {ECO:0000250}.
CC -!- INTERACTION:
CC Q96EQ0; Q9H172: ABCG4; NbExp=3; IntAct=EBI-744081, EBI-8584118;
CC Q96EQ0; Q7Z6V5: ADAT2; NbExp=3; IntAct=EBI-744081, EBI-2809203;
CC Q96EQ0; Q15848: ADIPOQ; NbExp=3; IntAct=EBI-744081, EBI-10827839;
CC Q96EQ0; O95994: AGR2; NbExp=6; IntAct=EBI-744081, EBI-712648;
CC Q96EQ0; Q8TD06: AGR3; NbExp=8; IntAct=EBI-744081, EBI-3925742;
CC Q96EQ0; Q12797-6: ASPH; NbExp=3; IntAct=EBI-744081, EBI-12092171;
CC Q96EQ0; P35070: BTC; NbExp=3; IntAct=EBI-744081, EBI-6590057;
CC Q96EQ0; P02745: C1QA; NbExp=3; IntAct=EBI-744081, EBI-1220209;
CC Q96EQ0; Q86Z23: C1QL4; NbExp=3; IntAct=EBI-744081, EBI-12062109;
CC Q96EQ0; Q9BXJ0: C1QTNF5; NbExp=3; IntAct=EBI-744081, EBI-19947914;
CC Q96EQ0; Q9BXI9: C1QTNF6; NbExp=3; IntAct=EBI-744081, EBI-10301084;
CC Q96EQ0; Q6UWT4: C5orf46; NbExp=3; IntAct=EBI-744081, EBI-11986083;
CC Q96EQ0; P27797: CALR; NbExp=3; IntAct=EBI-744081, EBI-1049597;
CC Q96EQ0; P16619: CCL3L3; NbExp=3; IntAct=EBI-744081, EBI-12934095;
CC Q96EQ0; Q8TD46-4: CD200R1; NbExp=3; IntAct=EBI-744081, EBI-12824513;
CC Q96EQ0; P04234: CD3D; NbExp=3; IntAct=EBI-744081, EBI-3862416;
CC Q96EQ0; P34810: CD68; NbExp=3; IntAct=EBI-744081, EBI-2826276;
CC Q96EQ0; P40259: CD79B; NbExp=3; IntAct=EBI-744081, EBI-2873732;
CC Q96EQ0; Q8TCZ2: CD99L2; NbExp=6; IntAct=EBI-744081, EBI-2824782;
CC Q96EQ0; P55291: CDH15; NbExp=3; IntAct=EBI-744081, EBI-10215061;
CC Q96EQ0; P30085-3: CMPK1; NbExp=3; IntAct=EBI-744081, EBI-23373346;
CC Q96EQ0; Q03692: COL10A1; NbExp=3; IntAct=EBI-744081, EBI-2528309;
CC Q96EQ0; A0A0S2Z3K0: COL1A2; NbExp=3; IntAct=EBI-744081, EBI-16431143;
CC Q96EQ0; P08123: COL1A2; NbExp=3; IntAct=EBI-744081, EBI-983038;
CC Q96EQ0; Q9Y215: COLQ; NbExp=3; IntAct=EBI-744081, EBI-1637847;
CC Q96EQ0; P49747: COMP; NbExp=3; IntAct=EBI-744081, EBI-2531022;
CC Q96EQ0; Q68CJ9: CREB3L3; NbExp=3; IntAct=EBI-744081, EBI-852194;
CC Q96EQ0; P0DML2: CSH1; NbExp=3; IntAct=EBI-744081, EBI-13375302;
CC Q96EQ0; P0DML3: CSH2; NbExp=3; IntAct=EBI-744081, EBI-12167441;
CC Q96EQ0; P78358: CTAG1B; NbExp=3; IntAct=EBI-744081, EBI-1188472;
CC Q96EQ0; Q9UHQ9: CYB5R1; NbExp=3; IntAct=EBI-744081, EBI-953870;
CC Q96EQ0; Q01524: DEFA6; NbExp=3; IntAct=EBI-744081, EBI-10222451;
CC Q96EQ0; O95424: DEXI; NbExp=3; IntAct=EBI-744081, EBI-724515;
CC Q96EQ0; Q6E0U4: DMKN; NbExp=3; IntAct=EBI-744081, EBI-7943171;
CC Q96EQ0; Q16610: ECM1; NbExp=3; IntAct=EBI-744081, EBI-947964;
CC Q96EQ0; O95967: EFEMP2; NbExp=8; IntAct=EBI-744081, EBI-743414;
CC Q96EQ0; Q9ULC0-2: EMCN; NbExp=5; IntAct=EBI-744081, EBI-12164849;
CC Q96EQ0; P30040: ERP29; NbExp=6; IntAct=EBI-744081, EBI-946830;
CC Q96EQ0; Q9HBU6: ETNK1; NbExp=3; IntAct=EBI-744081, EBI-2834493;
CC Q96EQ0; Q9H8M9: EVA1A; NbExp=3; IntAct=EBI-744081, EBI-715362;
CC Q96EQ0; P35555: FBN1; NbExp=3; IntAct=EBI-744081, EBI-2505934;
CC Q96EQ0; Q9NSA1: FGF21; NbExp=3; IntAct=EBI-744081, EBI-3909329;
CC Q96EQ0; O75084: FZD7; NbExp=3; IntAct=EBI-744081, EBI-746917;
CC Q96EQ0; Q8NCW6-2: GALNT11; NbExp=3; IntAct=EBI-744081, EBI-13364322;
CC Q96EQ0; Q92820: GGH; NbExp=3; IntAct=EBI-744081, EBI-3045534;
CC Q96EQ0; P09681: GIP; NbExp=3; IntAct=EBI-744081, EBI-8588553;
CC Q96EQ0; Q96SL4: GPX7; NbExp=5; IntAct=EBI-744081, EBI-749411;
CC Q96EQ0; P02724: GYPA; NbExp=3; IntAct=EBI-744081, EBI-702665;
CC Q96EQ0; Q96GW1: HSP90B1; NbExp=3; IntAct=EBI-744081, EBI-12885352;
CC Q96EQ0; P48723: HSPA13; NbExp=5; IntAct=EBI-744081, EBI-750892;
CC Q96EQ0; P08887: IL6R; NbExp=3; IntAct=EBI-744081, EBI-299383;
CC Q96EQ0; P40189: IL6ST; NbExp=4; IntAct=EBI-744081, EBI-1030834;
CC Q96EQ0; Q17RA0: IL6ST; NbExp=3; IntAct=EBI-744081, EBI-10238517;
CC Q96EQ0; Q8IWB1: ITPRIP; NbExp=3; IntAct=EBI-744081, EBI-2556412;
CC Q96EQ0; Q6GPH6-2: ITPRIPL1; NbExp=3; IntAct=EBI-744081, EBI-12337095;
CC Q96EQ0; Q9UJ90: KCNE5; NbExp=3; IntAct=EBI-744081, EBI-11981259;
CC Q96EQ0; P04264: KRT1; NbExp=3; IntAct=EBI-744081, EBI-298429;
CC Q96EQ0; O43561-2: LAT; NbExp=3; IntAct=EBI-744081, EBI-8070286;
CC Q96EQ0; P80188: LCN2; NbExp=3; IntAct=EBI-744081, EBI-11911016;
CC Q96EQ0; P01229: LHB; NbExp=3; IntAct=EBI-744081, EBI-11659791;
CC Q96EQ0; P25791-3: LMO2; NbExp=3; IntAct=EBI-744081, EBI-11959475;
CC Q96EQ0; Q969H8: MYDGF; NbExp=3; IntAct=EBI-744081, EBI-718622;
CC Q96EQ0; Q8IW45: NAXD; NbExp=3; IntAct=EBI-744081, EBI-8650724;
CC Q96EQ0; Q13232: NME3; NbExp=5; IntAct=EBI-744081, EBI-713684;
CC Q96EQ0; Q99650: OSMR; NbExp=3; IntAct=EBI-744081, EBI-2804080;
CC Q96EQ0; Q5JUK9: PAGE3; NbExp=3; IntAct=EBI-744081, EBI-10244544;
CC Q96EQ0; Q15084: PDIA6; NbExp=3; IntAct=EBI-744081, EBI-1043087;
CC Q96EQ0; O00264: PGRMC1; NbExp=3; IntAct=EBI-744081, EBI-1045534;
CC Q96EQ0; O00592-2: PODXL; NbExp=3; IntAct=EBI-744081, EBI-12407415;
CC Q96EQ0; P23284: PPIB; NbExp=4; IntAct=EBI-744081, EBI-359252;
CC Q96EQ0; P45877: PPIC; NbExp=3; IntAct=EBI-744081, EBI-953909;
CC Q96EQ0; Q96NZ9: PRAP1; NbExp=3; IntAct=EBI-744081, EBI-2116102;
CC Q96EQ0; A5D903: PRB1; NbExp=3; IntAct=EBI-744081, EBI-10173935;
CC Q96EQ0; Q04118: PRB3; NbExp=3; IntAct=EBI-744081, EBI-13360404;
CC Q96EQ0; Q16378: PRR4; NbExp=3; IntAct=EBI-744081, EBI-738624;
CC Q96EQ0; Q9UIG4: PSORS1C2; NbExp=3; IntAct=EBI-744081, EBI-11974061;
CC Q96EQ0; Q9Y5P3: RAI2; NbExp=5; IntAct=EBI-744081, EBI-746228;
CC Q96EQ0; Q15293: RCN1; NbExp=3; IntAct=EBI-744081, EBI-948278;
CC Q96EQ0; Q5GAN6: RNASE10; NbExp=3; IntAct=EBI-744081, EBI-12423312;
CC Q96EQ0; P50876: RNF144A; NbExp=3; IntAct=EBI-744081, EBI-2340657;
CC Q96EQ0; Q96K19-5: RNF170; NbExp=3; IntAct=EBI-744081, EBI-12055631;
CC Q96EQ0; P31431: SDC4; NbExp=3; IntAct=EBI-744081, EBI-3913237;
CC Q96EQ0; Q9HCN8: SDF2L1; NbExp=3; IntAct=EBI-744081, EBI-2339921;
CC Q96EQ0; Q8WWX9: SELENOM; NbExp=5; IntAct=EBI-744081, EBI-10277687;
CC Q96EQ0; P05121: SERPINE1; NbExp=6; IntAct=EBI-744081, EBI-953978;
CC Q96EQ0; P36955: SERPINF1; NbExp=3; IntAct=EBI-744081, EBI-2932733;
CC Q96EQ0; O75830: SERPINI2; NbExp=4; IntAct=EBI-744081, EBI-750144;
CC Q96EQ0; Q16586: SGCA; NbExp=3; IntAct=EBI-744081, EBI-5663553;
CC Q96EQ0; O43765: SGTA; NbExp=3; IntAct=EBI-744081, EBI-347996;
CC Q96EQ0; Q8N114-3: SHISA5; NbExp=3; IntAct=EBI-744081, EBI-13369834;
CC Q96EQ0; Q9H173: SIL1; NbExp=3; IntAct=EBI-744081, EBI-2840325;
CC Q96EQ0; P03973: SLPI; NbExp=3; IntAct=EBI-744081, EBI-355293;
CC Q96EQ0; P08294: SOD3; NbExp=3; IntAct=EBI-744081, EBI-10195782;
CC Q96EQ0; O60575: SPINK4; NbExp=3; IntAct=EBI-744081, EBI-13336697;
CC Q96EQ0; P10451: SPP1; NbExp=3; IntAct=EBI-744081, EBI-723648;
CC Q96EQ0; P10124: SRGN; NbExp=3; IntAct=EBI-744081, EBI-744915;
CC Q96EQ0; Q9BT88: SYT11; NbExp=3; IntAct=EBI-744081, EBI-751770;
CC Q96EQ0; Q9H2B2: SYT4; NbExp=3; IntAct=EBI-744081, EBI-751132;
CC Q96EQ0; P04155: TFF1; NbExp=5; IntAct=EBI-744081, EBI-743871;
CC Q96EQ0; Q6UXF1: TMEM108; NbExp=3; IntAct=EBI-744081, EBI-7100456;
CC Q96EQ0; Q8N131: TMEM123; NbExp=3; IntAct=EBI-744081, EBI-749248;
CC Q96EQ0; Q9BVT8: TMUB1; NbExp=3; IntAct=EBI-744081, EBI-11425701;
CC Q96EQ0; Q9NS68-2: TNFRSF19; NbExp=3; IntAct=EBI-744081, EBI-12089038;
CC Q96EQ0; O75888-3: TNFSF13; NbExp=3; IntAct=EBI-744081, EBI-12856452;
CC Q96EQ0; O95881: TXNDC12; NbExp=6; IntAct=EBI-744081, EBI-2564581;
CC Q96EQ0; P11441: UBL4A; NbExp=4; IntAct=EBI-744081, EBI-356983;
CC Q96EQ0; O75631: UPK3A; NbExp=3; IntAct=EBI-744081, EBI-10188907;
CC Q96EQ0; P49767: VEGFC; NbExp=3; IntAct=EBI-744081, EBI-3405539;
CC Q96EQ0; Q2TAL6: VWC2; NbExp=3; IntAct=EBI-744081, EBI-11957238;
CC Q96EQ0; Q8WWY7: WFDC12; NbExp=3; IntAct=EBI-744081, EBI-11958577;
CC Q96EQ0; O60844: ZG16; NbExp=5; IntAct=EBI-744081, EBI-746479;
CC Q96EQ0; Q96DA0: ZG16B; NbExp=5; IntAct=EBI-744081, EBI-953824;
CC Q96EQ0; A0A1U9X8X8; NbExp=3; IntAct=EBI-744081, EBI-17234977;
CC -!- SIMILARITY: Belongs to the SGT family. {ECO:0000305}.
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DR EMBL; AF368281; AAP29459.1; -; mRNA.
DR EMBL; AK096321; BAC04761.1; -; mRNA.
DR EMBL; BC012044; AAH12044.1; -; mRNA.
DR CCDS; CCDS3988.1; -.
DR RefSeq; NP_061945.1; NM_019072.2.
DR RefSeq; XP_005248605.1; XM_005248548.3.
DR AlphaFoldDB; Q96EQ0; -.
DR SMR; Q96EQ0; -.
DR BioGRID; 120042; 203.
DR IntAct; Q96EQ0; 192.
DR MINT; Q96EQ0; -.
DR STRING; 9606.ENSP00000370395; -.
DR GlyGen; Q96EQ0; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; Q96EQ0; -.
DR PhosphoSitePlus; Q96EQ0; -.
DR BioMuta; SGTB; -.
DR DMDM; 41018109; -.
DR EPD; Q96EQ0; -.
DR jPOST; Q96EQ0; -.
DR MassIVE; Q96EQ0; -.
DR MaxQB; Q96EQ0; -.
DR PaxDb; Q96EQ0; -.
DR PeptideAtlas; Q96EQ0; -.
DR PRIDE; Q96EQ0; -.
DR ProteomicsDB; 76440; -.
DR Antibodypedia; 23800; 115 antibodies from 20 providers.
DR DNASU; 54557; -.
DR Ensembl; ENST00000381007.9; ENSP00000370395.4; ENSG00000197860.10.
DR GeneID; 54557; -.
DR KEGG; hsa:54557; -.
DR MANE-Select; ENST00000381007.9; ENSP00000370395.4; NM_019072.3; NP_061945.1.
DR UCSC; uc003jud.4; human.
DR CTD; 54557; -.
DR DisGeNET; 54557; -.
DR GeneCards; SGTB; -.
DR HGNC; HGNC:23567; SGTB.
DR HPA; ENSG00000197860; Tissue enhanced (brain).
DR neXtProt; NX_Q96EQ0; -.
DR OpenTargets; ENSG00000197860; -.
DR PharmGKB; PA134957805; -.
DR VEuPathDB; HostDB:ENSG00000197860; -.
DR eggNOG; KOG0553; Eukaryota.
DR GeneTree; ENSGT00940000158321; -.
DR HOGENOM; CLU_044224_0_0_1; -.
DR InParanoid; Q96EQ0; -.
DR OMA; ASGQHEK; -.
DR OrthoDB; 687493at2759; -.
DR PhylomeDB; Q96EQ0; -.
DR TreeFam; TF313092; -.
DR PathwayCommons; Q96EQ0; -.
DR SignaLink; Q96EQ0; -.
DR BioGRID-ORCS; 54557; 4 hits in 1076 CRISPR screens.
DR ChiTaRS; SGTB; human.
DR GenomeRNAi; 54557; -.
DR Pharos; Q96EQ0; Tbio.
DR PRO; PR:Q96EQ0; -.
DR Proteomes; UP000005640; Chromosome 5.
DR RNAct; Q96EQ0; protein.
DR Bgee; ENSG00000197860; Expressed in endothelial cell and 187 other tissues.
DR ExpressionAtlas; Q96EQ0; baseline and differential.
DR Genevisible; Q96EQ0; HS.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0072380; C:TRC complex; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0006620; P:post-translational protein targeting to endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR032374; SGTA_dimer.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF16546; SGTA_dimer; 1.
DR Pfam; PF00515; TPR_1; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Acetylation; Chaperone; Phosphoprotein; Reference proteome; Repeat;
KW TPR repeat.
FT CHAIN 1..304
FT /note="Small glutamine-rich tetratricopeptide repeat-
FT containing protein beta"
FT /id="PRO_0000106368"
FT REPEAT 15..49
FT /note="TPR 1"
FT REPEAT 85..118
FT /note="TPR 2"
FT REPEAT 119..152
FT /note="TPR 3"
FT REPEAT 153..186
FT /note="TPR 4"
FT MOD_RES 131
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:O43765"
FT MOD_RES 293
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O43765"
FT MOD_RES 295
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18669648"
FT MOD_RES 297
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18669648,
FT ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163"
SQ SEQUENCE 304 AA; 33429 MW; 10819155C4E150FB CRC64;
MSSIKHLVYA VIRFLREQSQ MDTYTSDEQE SLEVAIQCLE TVFKISPEDT HLAVSQPLTE
MFTSSFCKND VLPLSNSVPE DVGKADQLKD EGNNHMKEEN YAAAVDCYTQ AIELDPNNAV
YYCNRAAAQS KLGHYTDAIK DCEKAIAIDS KYSKAYGRMG LALTALNKFE EAVTSYQKAL
DLDPENDSYK SNLKIAEQKL REVSSPTGTG LSFDMASLIN NPAFISMAAS LMQNPQVQQL
MSGMMTNAIG GPAAGVGGLT DLSSLIQAGQ QFAQQIQQQN PELIEQLRNH IRSRSFSSSA
EEHS
