ID   SGYQP_PINMG             Reviewed;         332 AA.
AC   H2A0L9;
DT   13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   03-AUG-2022, entry version 20.
DE   RecName: Full=Serine, glycine, tyrosine and glutamine-rich protein;
DE   AltName: Full=Cement-like protein;
DE   Flags: Precursor;
OS   Margaritifera margaritifera (Freshwater pearl mussel).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Pterioida; Pterioidea; Pteriidae; Pinctada.
OX   NCBI_TaxID=102329;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION.
RC   TISSUE=Mantle;
RX   PubMed=21040589; DOI=10.1186/1471-2164-11-613;
RA   Joubert C., Piquemal D., Marie B., Manchon L., Pierrat F.,
RA   Zanella-Cleon I., Cochennec-Laureau N., Gueguen Y., Montagnani C.;
RT   "Transcriptome and proteome analysis of Pinctada margaritifera calcifying
RT   mantle and shell: focus on biomineralization.";
RL   BMC Genomics 11:613-613(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 106-150; 159-187 AND 300-322, SUBCELLULAR LOCATION, AND
RP   TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23213212; DOI=10.1073/pnas.1210552109;
RA   Marie B., Joubert C., Tayale A., Zanella-Cleon I., Belliard C.,
RA   Piquemal D., Cochennec-Laureau N., Marin F., Gueguen Y., Montagnani C.;
RT   "Different secretory repertoires control the biomineralization processes of
RT   prism and nacre deposition of the pearl oyster shell.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:20986-20991(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23213212}.
CC   -!- TISSUE SPECIFICITY: Prismatic layer of shell (at protein level).
CC       Expressed primarily in the mantle with highest level in the mantle edge
CC       and lower level in the mantle pallium. {ECO:0000269|PubMed:23213212}.
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DR   EMBL; HE610386; CCE46160.1; -; mRNA.
DR   AlphaFoldDB; H2A0L9; -.
DR   PRIDE; H2A0L9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..332
FT                   /note="Serine, glycine, tyrosine and glutamine-rich
FT                   protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000417944"
FT   REGION          39..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   332 AA;  32498 MW;  700C424052262BC5 CRC64;
     MMKTVLLLVV LVGVAYCDDD GWDMGNFFQQ YHQWQQQISS SSSSSSSSGG GGSSGGGASG
     GGGGGGSSGG GGASGGGGGG SSGGGGLTKV VLKAGGGGRG GGGIVKSVGG GGGGVTKLVA
     AGGASGGGSV SGGGGGGLAL LAGGSAAGGG RSGVVTVSKQ PIIINRQVTH VNTGGSGGGV
     GGGFGGGRGG FGYGLYGGHH HYNPCGYGQV YSYYYGCQSI YKQPARQVYH QPIYQPVQTV
     YQPVQYYQQP YQYQHSYGQA SHAYQPQTTK YISYSYPQYS SQGSYPIVAG GSAGGFASAR
     SGGFGLSSGG IGGHSSYPLS VFKHAKGEKY KL