ID   SH3L3_BOVIN             Reviewed;          93 AA.
AC   Q3ZCL8;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3;
GN   Name=SH3BGRL3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could act as a modulator of glutaredoxin biological activity.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SH3BGR family. {ECO:0000305}.
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DR   EMBL; BC102048; AAI02049.1; -; mRNA.
DR   RefSeq; NP_001029935.1; NM_001034763.2.
DR   AlphaFoldDB; Q3ZCL8; -.
DR   BMRB; Q3ZCL8; -.
DR   SMR; Q3ZCL8; -.
DR   IntAct; Q3ZCL8; 1.
DR   STRING; 9913.ENSBTAP00000012599; -.
DR   PaxDb; Q3ZCL8; -.
DR   PeptideAtlas; Q3ZCL8; -.
DR   PRIDE; Q3ZCL8; -.
DR   Ensembl; ENSBTAT00000012599; ENSBTAP00000012599; ENSBTAG00000009580.
DR   GeneID; 614672; -.
DR   KEGG; bta:614672; -.
DR   CTD; 83442; -.
DR   VEuPathDB; HostDB:ENSBTAG00000009580; -.
DR   VGNC; VGNC:106924; SH3BGRL3.
DR   eggNOG; KOG4023; Eukaryota.
DR   GeneTree; ENSGT00940000157260; -.
DR   HOGENOM; CLU_127988_0_0_1; -.
DR   InParanoid; Q3ZCL8; -.
DR   OMA; FFNEDQY; -.
DR   OrthoDB; 1508713at2759; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000009580; Expressed in monocyte and 105 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   CDD; cd03030; GRX_SH3BGR; 1.
DR   InterPro; IPR006993; Glut_rich_SH3-bd.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF04908; SH3BGR; 1.
DR   PIRSF; PIRSF008142; SH3-bind_E-rich_L; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cytoplasm; Nucleus; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H299"
FT   CHAIN           2..93
FT                   /note="SH3 domain-binding glutamic acid-rich-like protein
FT                   3"
FT                   /id="PRO_0000305925"
FT   DOMAIN          2..93
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H299"
SQ   SEQUENCE   93 AA;  10438 MW;  C30BE3251D5B82CC CRC64;
     MSGLRVYSTS VTGSREIKSQ QSEVTRILDG KRIQYQLVDI SQDNALRDEM RALAGNPKAT
     PPQIVNGDQY CGDYELFVEA VEQNTLQEFL KLA