ID   SH3L3_PONAB             Reviewed;          93 AA.
AC   Q5RC61;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3;
GN   Name=SH3BGRL3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could act as a modulator of glutaredoxin biological activity.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SH3BGR family. {ECO:0000305}.
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DR   EMBL; CR858420; CAH90649.1; -; mRNA.
DR   RefSeq; NP_001125350.1; NM_001131878.1.
DR   AlphaFoldDB; Q5RC61; -.
DR   BMRB; Q5RC61; -.
DR   SMR; Q5RC61; -.
DR   STRING; 9601.ENSPPYP00000001951; -.
DR   GeneID; 100172252; -.
DR   KEGG; pon:100172252; -.
DR   CTD; 83442; -.
DR   eggNOG; KOG4023; Eukaryota.
DR   InParanoid; Q5RC61; -.
DR   OrthoDB; 1508713at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd03030; GRX_SH3BGR; 1.
DR   InterPro; IPR006993; Glut_rich_SH3-bd.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF04908; SH3BGR; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cytoplasm; Nucleus; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H299"
FT   CHAIN           2..93
FT                   /note="SH3 domain-binding glutamic acid-rich-like protein
FT                   3"
FT                   /id="PRO_0000305926"
FT   DOMAIN          2..93
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H299"
SQ   SEQUENCE   93 AA;  10481 MW;  C3141D3AFCA59D32 CRC64;
     MSGRRVYSTS VTGSREIKSQ QSEVTRILDG KRIQYQLVDI SQDNALRDEM RALAGNPKAT
     PPQIVNGDQY CGDYELFVEA VEQNTLQEFL KLA