SH3Y1_BOVIN
ID SH3Y1_BOVIN Reviewed; 341 AA.
AC Q3SZ01;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=SH3 domain-containing YSC84-like protein 1;
GN Name=SH3YL1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Uterus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with SH3D19. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SH3YL1 family. {ECO:0000305}.
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DR EMBL; BC103306; AAI03307.1; -; mRNA.
DR RefSeq; NP_001029779.1; NM_001034607.1.
DR AlphaFoldDB; Q3SZ01; -.
DR SMR; Q3SZ01; -.
DR STRING; 9913.ENSBTAP00000030484; -.
DR PaxDb; Q3SZ01; -.
DR Ensembl; ENSBTAT00000030504; ENSBTAP00000030484; ENSBTAG00000020495.
DR GeneID; 534337; -.
DR KEGG; bta:534337; -.
DR CTD; 26751; -.
DR VEuPathDB; HostDB:ENSBTAG00000020495; -.
DR VGNC; VGNC:34584; SH3YL1.
DR eggNOG; KOG1843; Eukaryota.
DR GeneTree; ENSGT00510000048137; -.
DR InParanoid; Q3SZ01; -.
DR OMA; NDAMYND; -.
DR OrthoDB; 1090526at2759; -.
DR Proteomes; UP000009136; Chromosome 8.
DR Bgee; ENSBTAG00000020495; Expressed in prostate gland and 98 other tissues.
DR GO; GO:0032587; C:ruffle membrane; IBA:GO_Central.
DR GO; GO:0019902; F:phosphatase binding; IEA:Ensembl.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:Ensembl.
DR GO; GO:1900027; P:regulation of ruffle assembly; IEA:Ensembl.
DR CDD; cd11841; SH3_SH3YL1_like; 1.
DR CDD; cd11525; SYLF_SH3YL1_like; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035511; SH3YL1_SH3.
DR InterPro; IPR033643; SYLF_SH3YL1-like.
DR InterPro; IPR007461; Ysc84_actin-binding.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF04366; Ysc84; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SSF50044; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; SH3 domain.
FT CHAIN 1..341
FT /note="SH3 domain-containing YSC84-like protein 1"
FT /id="PRO_0000341559"
FT DOMAIN 282..341
FT /note="SH3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT REGION 221..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 37065 MW; 11253FAB1E27E084 CRC64;
MNNPIPSNLK SEAKKAAKIL REFTEITSRN GPDKIIPAHV IAKAKGLAIL SVIKAGFLVT
ARGGSGIVLA RLPDGKWSAP SAIGIAGLGG GFELGIEVSD LVIILNYDRA VEAFAKGGNL
TLGGNLTVAV GPLGRNLEGN VSLRSSAAVF TYCKSRGLFA GISLEGSCLI ERKETNRKFY
CQDIRAYDIL FGDITRPAQA EDLYEVLDSF TEKYEIEGQR VNARRAAREQ KKASAKLPPK
PSSRPEQSSA QVQLSSGSQS SRNEYNLYPE LSSYRERVGN SNQPIEVTAL YSFEGQQPGD
LNFQAGDRIT VISKTDSHFD WWEGKLRGRT GIFPANYVTM N