ID   SHCBB_XENLA             Reviewed;         698 AA.
AC   Q640F2;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=SHC SH2 domain-binding protein 1 homolog B;
GN   Name=shcbp1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in signaling pathways governing cellular
CC       proliferation. {ECO:0000250|UniProtKB:Q9Z179}.
CC   -!- SUBCELLULAR LOCATION: Midbody {ECO:0000250|UniProtKB:Q8NEM2}.
CC       Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q8NEM2}.
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DR   EMBL; BC082676; AAH82676.1; -; mRNA.
DR   RefSeq; NP_001087996.1; NM_001094527.1.
DR   AlphaFoldDB; Q640F2; -.
DR   SMR; Q640F2; -.
DR   DNASU; 494685; -.
DR   GeneID; 494685; -.
DR   KEGG; xla:494685; -.
DR   CTD; 494685; -.
DR   Xenbase; XB-GENE-5807734; shcbp1.L.
DR   OrthoDB; 1276823at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 494685; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   Gene3D; 2.160.20.10; -; 1.
DR   InterPro; IPR039448; Beta_helix.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   InterPro; IPR045140; SHCBP1-like.
DR   PANTHER; PTHR14695; PTHR14695; 1.
DR   Pfam; PF13229; Beta_helix; 1.
DR   SUPFAM; SSF51126; SSF51126; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Reference proteome; Repeat.
FT   CHAIN           1..698
FT                   /note="SHC SH2 domain-binding protein 1 homolog B"
FT                   /id="PRO_0000076318"
FT   REPEAT          480..502
FT                   /note="PbH1 1"
FT   REPEAT          503..524
FT                   /note="PbH1 2"
FT   REPEAT          532..554
FT                   /note="PbH1 3"
SQ   SEQUENCE   698 AA;  79593 MW;  E90A90536E8AF6E0 CRC64;
     MAEEEPLFPA LQEEDDFFRI NSDRCSEELQ DVKQVLFQEE GDSGSDYGSF KRLGKVLPRT
     VRAGNMLFPD LFQTNNLLFY ERFETYKDYM LGDCKPSEVK EFIAEYLEKA LEPSGWKAIW
     HTDVFDVLVE VTDVEFSSLN AIVRLCEPFL CESRVSSITH ESINDLLEVK DQRVPLQELR
     VVFDESGLYD QTALTIEHVR FFYQQIWRPW DEEEEDYFDY FVRCVEPRLR LHYDILEDRI
     PSGLVAEYRS LLLQSEAVYM QFTNLRNNLS NKDSDSEAEL DNVSMVEGMK MDDEMENLKR
     KLKLIKNPLL RYLFCYQRNS GSYNMQAKGP RPTGGKVIHV VSTSMSITML QCLTRERLQP
     ECSNKDLEIQ FHRDPLEAVN ACYEGDLVII CPGLYTIYGL INIMDSIEIE GYGLPDDVII
     EKKGKGDSFV DCNGAHVKIS NVKFVQHEAV EGIITIHSGT TELDNCVLQC ETTGVTVKKC
     AELLMKYSDL YGAKGAGMEI YPGSKCTLIG NGIHHCRDGI LIKDFIDVVY EIPKIIMENN
     VIHNNEGYAV VLVKPSPNFE KNSHTEELEG EHLDNNMIEE QASSNVLQPN LNEAMGVEDN
     AIEKSDHLEE EKSDPTIAKE EVECEYAIDC EEAEGNQVIA TELVANTRRK TQLHKKRLST
     LGIVTADDNN LTSQEIFVSI VGNQFKRNGK GSFGTFLF