SHE10_YEAS1
ID SHE10_YEAS1 Reviewed; 577 AA.
AC B3LHS1;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Outer spore wall assembly protein SHE10 {ECO:0000250|UniProtKB:P53075};
DE AltName: Full=Sensitivity to high expression protein 10 {ECO:0000250|UniProtKB:P53075};
DE Flags: Precursor;
GN Name=SHE10 {ECO:0000250|UniProtKB:P53075}; ORFNames=SCRG_01213;
OS Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=285006;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM11-1a;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA Kruglyak L.;
RT "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in spore wall assembly. May be a component of the
CC mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease
CC involved in the cleaving RNA transcripts to generate primers for DNA
CC replication in mitochondria. {ECO:0000250|UniProtKB:P53075}.
CC -!- SUBUNIT: Component of the mitochondria-localized RNase mitochondrial
CC RNA-processing (RNase MRP) composed of one single RNA encoded by the
CC NME1 gene and at least 31 proteins. Absent in the nucleus-localized
CC RNase MRP (NuMRP). {ECO:0000250|UniProtKB:P53075}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P53075}.
CC -!- SIMILARITY: Belongs to the SHE10 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408044; EDV10429.1; -; Genomic_DNA.
DR AlphaFoldDB; B3LHS1; -.
DR SMR; B3LHS1; -.
DR EnsemblFungi; EDV10429; EDV10429; SCRG_01213.
DR HOGENOM; CLU_023952_1_0_1; -.
DR Proteomes; UP000008335; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Coiled coil; Mitochondrion; Ribonucleoprotein; Signal; Sporulation.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..577
FT /note="Outer spore wall assembly protein SHE10"
FT /id="PRO_0000408911"
FT REGION 525..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 379..416
FT /evidence="ECO:0000255"
FT COILED 513..561
FT /evidence="ECO:0000255"
FT COMPBIAS 525..551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 66809 MW; 24D80C2C8CCFEC6F CRC64;
MGKLIKLITT LTVLVSLLQY CCEFNSGSIS CERTQTLCHY TNPRVWNTYF SRNCELYKNK
VSPGFDIVAR KYDTAVKPVI DDATVKVNKV AIQPAFKVIH SQCKKWNCGK YYQLVRSPMV
KTRRFFFAKY NAFVKPNIDK FFTAEFRSHL KERILKCKNI GHYYFTITSR CIKSKYDFIV
GNTEEKLMGK FKNKDTHGIH GSVTHEPSSE DMVLTVSTME SDEEELTTTS TQTVVETITL
DQEEASAVAN HAHDDEASTD VEDSTDVNVN EQALLQEDFD MWSETILQKT QDVIQLFEKD
VSKYIHGKLV EEANHFKAKF QSLDDKSKKF FSKISLAIND IECVEGIDSE TGKKIFFDKS
GSTEISQYIT RELVREYFNE TRSTLDELTN AMEKDLSEIT DEIEKKVNAI REENVEVFEE
WGDIIVNEWS KRMAYVDVIN AHMGADDDTT LDEEKAKSSV NWKKFLKGKK QIIESRDKLA
HHSADLSRVN AFRQKVQKKI LSFTQESGEF LYILRSKANL QFQERERKER ERKEREKAAA
EEFQRQQELL LQQEEEDEED VSYTSTSTIT TTTTMTL
