ID   SHE10_YEAS8             Reviewed;         577 AA.
AC   C8Z826;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Outer spore wall assembly protein SHE10 {ECO:0000250|UniProtKB:P53075};
DE   AltName: Full=Sensitivity to high expression protein 10 {ECO:0000250|UniProtKB:P53075};
DE   Flags: Precursor;
GN   Name=SHE10 {ECO:0000250|UniProtKB:P53075}; ORFNames=EC1118_1G1_0419g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Involved in spore wall assembly. May be a component of the
CC       mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease
CC       involved in the cleaving RNA transcripts to generate primers for DNA
CC       replication in mitochondria. {ECO:0000250|UniProtKB:P53075}.
CC   -!- SUBUNIT: Component of the mitochondria-localized RNase mitochondrial
CC       RNA-processing (RNase MRP) composed of one single RNA encoded by the
CC       NME1 gene and at least 31 proteins. Absent in the nucleus-localized
CC       RNase MRP (NuMRP). {ECO:0000250|UniProtKB:P53075}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P53075}.
CC   -!- SIMILARITY: Belongs to the SHE10 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN393070; CAY79542.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8Z826; -.
DR   EnsemblFungi; CAY79542; CAY79542; EC1118_1G1_0419g.
DR   HOGENOM; CLU_023952_1_0_1; -.
DR   Proteomes; UP000000286; Chromosome VII, Scaffold EC1118_1G1.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Coiled coil; Mitochondrion; Ribonucleoprotein; Signal; Sporulation.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..577
FT                   /note="Outer spore wall assembly protein SHE10"
FT                   /id="PRO_0000408914"
FT   REGION          525..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          379..416
FT                   /evidence="ECO:0000255"
FT   COILED          513..561
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        525..552
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        563..577
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  66810 MW;  BA8399B70DE26AD4 CRC64;
     MGKLIKLITT LTVLVSLLQY CCEFNSGSIS CERTQTLCHY TNPRVWNTYF SRNCELYKNK
     VSPGFDIVAR KYDTAVKPVI DDATVKVNKA AIQPAFKVIH SQCKKWNCGK YYQLVRSPMV
     KTRRFFFAKY NAFVKPNLDK FFTAEFRSHL KERILKYKNI GHYYFTITSR CIKSKYDFTV
     GNTEEKLMGK FKNKDTHGIH GSVTREPSSE DMVLTVSTME SDEEELTTTS TQTVVETITL
     DQEEASAVAN HAHDDEASTD VEGSTDVNVN EQALLQEDFD MWSETILQKT QDVIQLFEKD
     VSKYINGKLV EEANHFKAKF QSLDDKSKKF FSKISLAIND IECVEGIDSE TGKKIFFDKS
     GSTEISQYIT RELVREYFNE TRSTLDELTN AMEKDLSEIT DEIEKKVNAI REENVEVFEE
     WGDIIVNEWS KRMAYVDVIN AHMGADDDTT LDEEKAKSSV NWKKFLKGKK QIIESRDKLA
     HHSADLSRVN AFRQKVQKKI LSFTQESGEF LYILRSKANL QFQERERKER ERKEREKAAA
     EEFQRQQELL RQQEEEDEED VSYTSTSTIT TTTTMTL