ID   SHE1_CANGA              Reviewed;         282 AA.
AC   Q6FUD9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Mitotic spindle-associated protein SHE1;
GN   Name=SHE1; OrderedLocusNames=CAGL0F04235g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May have a role related to the spindle integrity, which is
CC       essential for proper chromosome segregation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, spindle {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SHE1 family. {ECO:0000305}.
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DR   EMBL; CR380952; CAG59079.1; -; Genomic_DNA.
DR   RefSeq; XP_446155.1; XM_446155.1.
DR   AlphaFoldDB; Q6FUD9; -.
DR   PRIDE; Q6FUD9; -.
DR   EnsemblFungi; CAG59079; CAG59079; CAGL0F04235g.
DR   GeneID; 2887758; -.
DR   KEGG; cgr:CAGL0F04235g; -.
DR   CGD; CAL0131164; CAGL0F04235g.
DR   VEuPathDB; FungiDB:CAGL0F04235g; -.
DR   HOGENOM; CLU_986942_0_0_1; -.
DR   InParanoid; Q6FUD9; -.
DR   OMA; KINSAHR; -.
DR   Proteomes; UP000002428; Chromosome F.
DR   GO; GO:0005935; C:cellular bud neck; IEA:EnsemblFungi.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005880; C:nuclear microtubule; IEA:EnsemblFungi.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0008017; F:microtubule binding; IEA:EnsemblFungi.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000022; P:mitotic spindle elongation; IEA:EnsemblFungi.
DR   InterPro; IPR031401; She1.
DR   Pfam; PF17077; Msap1; 2.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm; Cytoskeleton;
KW   Mitosis; Reference proteome.
FT   CHAIN           1..282
FT                   /note="Mitotic spindle-associated protein SHE1"
FT                   /id="PRO_0000333421"
FT   REGION          28..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          207..229
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          242..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        242..270
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   282 AA;  32125 MW;  F5216BF904DBCD96 CRC64;
     MNENDSNEII EQLGISKRLG NSILDELNQR ASETNPLLRK HEDTDNEEER PAESTPTAHN
     LVFNKVHNLN FENLTDKDPD FTIHNDPLHK KKYKYSPIKR VPEVNEITKK IRRLKLRSSS
     NLSSSGGSPE KRTTNASNVE QKTELAPLKT PNFLRPTFNS MNRAKDTSHK VESSRRTYGN
     LLPPTSRAIP AVKEAVRQDY TKRSISIQLP RKSPAPPKIP EQRSISDSSS NVFERLYKQT
     TMSRSNSMAF DQQNRKQLPK SRTITGLSSV VGDKHRTFPS KH