SHGR6_ARATH
ID SHGR6_ARATH Reviewed; 1716 AA.
AC F4IP13; Q8GUF9; Q9ZQ92; Q9ZQ93;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Protein SHOOT GRAVITROPISM 6;
GN Name=SGR6; OrderedLocusNames=At2g36810; ORFNames=F13K3.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 980-1716.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 980-1716.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=9210330; DOI=10.1093/oxfordjournals.pcp.a029201;
RA Yamauchi Y., Fukaki H., Fujisawa H., Tasaka M.;
RT "Mutations in the SGR4, SGR5 and SGR6 loci of Arabidopsis thaliana alter
RT the shoot gravitropism.";
RL Plant Cell Physiol. 38:530-535(1997).
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=24486761; DOI=10.1093/pcp/pcu020;
RA Hashiguchi Y., Yano D., Nagafusa K., Kato T., Saito C., Uemura T., Ueda T.,
RA Nakano A., Tasaka M., Terao Morita M.;
RT "A unique HEAT repeat-containing protein SHOOT GRAVITROPISM6 is involved in
RT vacuolar membrane dynamics in gravity-sensing cells of Arabidopsis
RT inflorescence stem.";
RL Plant Cell Physiol. 55:811-822(2014).
CC -!- FUNCTION: Involved in inflorescence stems gravitropism, by modulating
CC vacuolar membrane (VMs) dynamics in gravity-sensing cells (e.g.
CC endodermal cells) during the amyloplast sedimentation process.
CC {ECO:0000269|PubMed:24486761, ECO:0000269|PubMed:9210330}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:24486761}.
CC -!- TISSUE SPECIFICITY: Expressed in roots (e.g. root cap of primary roots
CC and vascular tissues), hypocotyls, cotyledons (including in guard
CC cells), stems (e.g. epidermis, endodermis, phloem, developing metaxylem
CC and interfascicular cells). {ECO:0000269|PubMed:24486761}.
CC -!- DISRUPTION PHENOTYPE: Abnormal inflorescence stems gravitropism but
CC normal hypocotyl gravitropism. Impaired flexible and dynamic structure
CC of vacuolar membrane (VMs) leading to altered amyloplast sedimentation.
CC {ECO:0000269|PubMed:24486761, ECO:0000269|PubMed:9210330}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD20157.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAD20158.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAO00894.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAE99257.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006282; AAD20157.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC006282; AAD20158.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09300.1; -; Genomic_DNA.
DR EMBL; BT002534; AAO00894.1; ALT_INIT; mRNA.
DR EMBL; BT008796; AAP68235.1; -; mRNA.
DR EMBL; AK227220; BAE99257.1; ALT_INIT; mRNA.
DR PIR; A84785; A84785.
DR RefSeq; NP_181219.4; NM_129236.4.
DR AlphaFoldDB; F4IP13; -.
DR BioGRID; 3597; 1.
DR STRING; 3702.AT2G36810.1; -.
DR PaxDb; F4IP13; -.
DR PRIDE; F4IP13; -.
DR ProteomicsDB; 234522; -.
DR EnsemblPlants; AT2G36810.1; AT2G36810.1; AT2G36810.
DR GeneID; 818253; -.
DR Gramene; AT2G36810.1; AT2G36810.1; AT2G36810.
DR KEGG; ath:AT2G36810; -.
DR Araport; AT2G36810; -.
DR TAIR; locus:2040585; AT2G36810.
DR eggNOG; KOG2032; Eukaryota.
DR HOGENOM; CLU_002861_0_0_1; -.
DR InParanoid; F4IP13; -.
DR OrthoDB; 31329at2759; -.
DR PRO; PR:F4IP13; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4IP13; baseline and differential.
DR Genevisible; F4IP13; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:UniProtKB.
DR GO; GO:0009660; P:amyloplast organization; IMP:UniProtKB.
DR GO; GO:0009630; P:gravitropism; IMP:UniProtKB.
DR GO; GO:0009959; P:negative gravitropism; IMP:TAIR.
DR Gene3D; 1.25.10.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR045206; Maestro_heat-like_prot.
DR PANTHER; PTHR23120; PTHR23120; 1.
DR Pfam; PF12717; Cnd1; 1.
DR SUPFAM; SSF48371; SSF48371; 3.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Vacuole.
FT CHAIN 1..1716
FT /note="Protein SHOOT GRAVITROPISM 6"
FT /id="PRO_0000429061"
FT REPEAT 10..47
FT /note="HEAT 1"
FT REPEAT 144..181
FT /note="HEAT 2"
FT REPEAT 220..258
FT /note="HEAT 3"
FT REPEAT 263..300
FT /note="HEAT 4"
FT REPEAT 317..354
FT /note="HEAT 5"
FT REPEAT 381..418
FT /note="HEAT 6"
FT REPEAT 499..537
FT /note="HEAT 7"
FT REPEAT 552..591
FT /note="HEAT 8"
FT REPEAT 626..663
FT /note="HEAT 9"
FT REPEAT 667..705
FT /note="HEAT 10"
FT REPEAT 737..774
FT /note="HEAT 11"
FT REPEAT 785..822
FT /note="HEAT 12"
FT REPEAT 830..868
FT /note="HEAT 13"
FT REPEAT 910..947
FT /note="HEAT 14"
FT REPEAT 1013..1050
FT /note="HEAT 15"
FT REPEAT 1089..1128
FT /note="HEAT 16"
FT REPEAT 1148..1185
FT /note="HEAT 17"
FT REPEAT 1230..1269
FT /note="HEAT 18"
FT REPEAT 1372..1409
FT /note="HEAT 19"
FT REPEAT 1412..1449
FT /note="HEAT 20"
FT REPEAT 1451..1487
FT /note="HEAT 21"
FT REPEAT 1492..1529
FT /note="HEAT 22"
FT REPEAT 1537..1574
FT /note="HEAT 23"
FT REPEAT 1592..1629
FT /note="HEAT 24"
FT REPEAT 1653..1691
FT /note="HEAT 25"
SQ SEQUENCE 1716 AA; 189423 MW; 52BF5C210B84F538 CRC64;
MASSSLGSSI PAPEAVQLLV SSLADDSSVV REASMASLRD IASLNPLLVL DCCYAVSRGG
RRRFGNMAGV FQVMAFSVGA LEKGESDSVF MGKLAKIATA EIISSKELNA DWQRQASGLL
VSIGTHFPDL MMEEIFLHLS GPATAAPAMV QILADFASSD ALQFTPRLKG VLSKVSPILG
NVRDIHRPIF ANAFKCWSQA VWLYITDLTS DSPLDSDVMS FLNSVFELLL RVWAVSRDHK
VRVSTVDALG QMVGLITRTQ LKSALPRLIP AILELYKKDH DDALLATCSL HNLLNASLLS
ESGPPLLDFE DLTIVLSTLL PVIGINNERK RFSDISVGRK TYNEVQRCFL TVGLVYPEDL
FTFLLNKCKL KEDPLTFGAL CILKHLLPRL FEAWHSKRPL LVDTASSLLD EQSLAVRKAL
SELIVVMASH CYLVGPSGEL FVEYLVRHSA IGESDHLKAK GELVSPTQLR AVCGKGLLLL
TVTIPEMELS DFNAKEYMKL QYILWPFLLK MIIPKVYTGA VASVCRCITE LCRRRSSTTP
MLIECKARAD IPNPEELFTR LVVLLHNPLA KEQLASQILT VLGYLSPLFP KNISMFWQDE
IPKMKAYVYD TEDLKLDPTY QETWDDMIIN FLAESLDVTQ DADWVISLGN SFAKQYILYA
PDDDHAALLH RCIGILLQKV NDRAYVRDKI DWMYEQADIS IPANRLGLAK AMGLVAASHL
DTVLEKLKII VDNVGQSIFQ RILSLFSESY KTEDSDDIHA ALALMYGYAA KYAPSSVIEA
RIDALVGTNM LSRLLHVRQQ TAKQAVITAI DLLGRAVINA AETGATFPLK RRDQMLDYIL
TLMGRDENEG FAESSLEVLH TQALALNACT TLVSVEPKLT IETRNRVMKA TLGFFALPND
PSDVISPLID NLVTLLCAIL LTSGEDGRSR AEQLLHLLRQ LDQYVSSPID YQRKRGCVAV
HEMLLKFRKL CVGGYCALGC SGDCPHRKYA DRSMQGNFSN LPSVFLFPDR EVLCLGDRVI
TYLPRCADTN SEVRKISAQI LDQFFSISLS LPKAVLTSGL DSEDSYKALS SLEDVIAILK
SDASIDPSEV FNRIVSSICS LLTEHELVAA LHSCTAAICD KIRQSAEGAI QAVTEFVSRR
GSQLSDNDIS RTTHSLLSAA VHITDKNLRV EAIGAISALA ENTQSSIVFN EVLATAGKDI
VTKDITRMRG GWPMQDAFYA FSQHTELSVL FMEHLISILN RSSLVKSDSH KGENTSSSSE
THVEDDILQA AIFALTAFFR GGGKIGKKAV EKSYSSVVGA LTLQLGSCHG LASSGQQDPL
RVLLTSFQAF CECVGDLEMG KILARNGEQI EKEKWVGLIG DIAGCISIKR PKEVRHICMI
LTKALNRPQR FQREAAAAAL SEFIRYSGDF SSVMEEMVEA LCRHVSDDSP TVRRLCLRGL
VQMPSACMSH YTTQVIGVIL ALLDDLDESV QLTAVSCLLM VTESASNDAV EPILLNLSVR
LRNLQVSMDP KMRANAFSAL GALSKYATGG QREGFVEQIH STLPRLVVHL HDDDPSIRQA
CRVTLKRFAP LVDIINYSTL YDSRAFGSED RTDYENFVRD LSKHLVQESE RVDTYMASTI
QAFDAPWPVI QANAIHFSTT MLSLSEDQHI ISLYYPQVFE TLVSKMTRSQ DSVVRAACSS
AFGLLLRSSK STLWRGARLD GTDSGRKAND LESVKK
